MotifNRF1.H12INVITRO.0.PS.A
Gene (human)NRF1
(GeneCards)
Gene synonyms (human)
Gene (mouse)Nrf1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusnbnbYGCGCAbGCKCv
GC content68.31%
Information content (bits; total / per base)15.524 / 0.97
Data sourcesChIP-Seq + HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 20 (135) 0.987 0.994 0.963 0.982 0.985 0.995 6.027 6.662 489.469 733.721
Mouse 14 (87) 0.987 0.996 0.967 0.992 0.985 0.992 5.994 6.404 513.62 828.161

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.862 0.865 0.752 0.763 0.632 0.659
best 1.0 1.0 0.885 0.899 0.696 0.742

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.991 6.932 0.155 0.095
TF superclassYet undefined DNA-binding domains {0} (TFClass)
TF classUncharacterized {0.0} (TFClass)
TF familyNRF {0.0.6} (TFClass)
TF subfamily {0.0.6.0} (TFClass)
TFClass IDTFClass: 0.0.6.0.1
HGNCHGNC:7996
MGIMGI:1332235
EntrezGene (human)GeneID:4899
(SSTAR profile)
EntrezGene (mouse)GeneID:18181
(SSTAR profile)
UniProt ID (human)NRF1_HUMAN
UniProt ID (mouse)NRF1_MOUSE
UniProt AC (human)Q16656
(TFClass)
UniProt AC (mouse)Q9WU00
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 20 human, 14 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01190.0311.0279.0220.0
02159.0394.0208.0239.0
03232.0312.0264.0192.0
04103.0495.0238.0164.0
0554.0161.036.0749.0
0683.03.0914.00.0
077.0987.06.00.0
087.02.0988.03.0
090.01000.00.00.0
10985.01.013.01.0
1178.0133.0327.0462.0
1226.042.0913.019.0
1341.0854.09.096.0
1430.064.0753.0153.0
156.0778.034.0182.0
16471.0201.0210.0118.0
PFM
ACGT
010.190.3110.2790.22
020.1590.3940.2080.239
030.2320.3120.2640.192
040.1030.4950.2380.164
050.0540.1610.0360.749
060.0830.0030.9140.0
070.0070.9870.0060.0
080.0070.0020.9880.003
090.01.00.00.0
100.9850.0010.0130.001
110.0780.1330.3270.462
120.0260.0420.9130.019
130.0410.8540.0090.096
140.030.0640.7530.153
150.0060.7780.0340.182
160.4710.2010.210.118
PWM
ACGT
01-0.2720.2170.109-0.127
02-0.4490.452-0.183-0.045
03-0.0740.220.054-0.262
04-0.8770.68-0.049-0.418
05-1.508-0.436-1.8981.093
06-1.089-3.9751.291-4.982
07-3.3621.368-3.484-4.982
08-3.362-4.2131.369-3.975
09-4.9821.381-4.982-4.982
101.366-4.525-2.839-4.525
11-1.15-0.6250.2670.611
12-2.206-1.751.29-2.497
13-1.7741.224-3.156-0.946
14-2.071-1.3431.098-0.487
15-3.4841.131-1.952-0.315
160.63-0.216-0.173-0.743
Standard thresholds
P-value Threshold
0.001 2.37146
0.0005 3.68056
0.0001 6.38696