MotifNR6A1.H12INVIVO.2.SM.B
Gene (human)NR6A1
(GeneCards)
Gene synonyms (human)GCNF
Gene (mouse)Nr6a1
Gene synonyms (mouse)Gcnf
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length19
ConsensusnddYSAAGKTCAAGKKYRn
GC content46.14%
Information content (bits; total / per base)20.246 / 1.066
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9502

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.778 0.793 0.683 0.697 0.748 0.759 2.959 3.089 169.509 178.022

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.98 0.981 0.79 0.813 0.646 0.685
best 1.0 1.0 0.828 0.85 0.663 0.708
Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.828 0.85 0.663 0.708
best 1.0 1.0 0.828 0.85 0.663 0.708
Non-Methyl HT-SELEX, 1 experiments median 0.961 0.962 0.751 0.775 0.628 0.663
best 0.961 0.962 0.751 0.775 0.628 0.663
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyGCNF (NR6) {2.1.6} (TFClass)
TF subfamily {2.1.6.0} (TFClass)
TFClass IDTFClass: 2.1.6.0.1
HGNCHGNC:7985
MGIMGI:1352459
EntrezGene (human)GeneID:2649
(SSTAR profile)
EntrezGene (mouse)GeneID:14536
(SSTAR profile)
UniProt ID (human)NR6A1_HUMAN
UniProt ID (mouse)NR6A1_MOUSE
UniProt AC (human)Q15406
(TFClass)
UniProt AC (mouse)Q64249
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013262.51934.52634.51670.5
021524.01460.04835.01683.0
031311.01227.04414.02550.0
04737.01416.01059.06290.0
05617.07287.01032.0566.0
068931.066.0379.0126.0
079099.0164.0157.082.0
088.07.09425.062.0
0934.07.04649.04812.0
103.080.026.09393.0
113.09395.041.063.0
129482.00.011.09.0
138930.0280.069.0223.0
14118.0134.09020.0230.0
15246.0115.05322.03819.0
16420.0735.01441.06906.0
17247.07372.0556.01327.0
186424.75535.751961.75579.75
193015.52294.51754.52437.5
PFM
ACGT
010.3430.2040.2770.176
020.160.1540.5090.177
030.1380.1290.4650.268
040.0780.1490.1110.662
050.0650.7670.1090.06
060.940.0070.040.013
070.9580.0170.0170.009
080.0010.0010.9920.007
090.0040.0010.4890.506
100.00.0080.0030.989
110.00.9890.0040.007
120.9980.00.0010.001
130.940.0290.0070.023
140.0120.0140.9490.024
150.0260.0120.560.402
160.0440.0770.1520.727
170.0260.7760.0590.14
180.6760.0560.2060.061
190.3170.2410.1850.257
PWM
ACGT
010.317-0.2050.103-0.352
02-0.443-0.4860.71-0.344
03-0.594-0.660.6190.071
04-1.168-0.517-0.8070.973
05-1.3451.12-0.832-1.431
061.324-3.55-1.83-2.92
071.342-2.66-2.703-3.34
08-5.443-5.5451.377-3.611
09-4.182-5.5450.6710.705
10-6.108-3.364-4.4311.374
11-6.1081.374-4.006-3.595
121.383-6.945-5.187-5.35
131.324-2.131-3.507-2.357
14-2.984-2.8591.334-2.326
15-2.259-3.0090.8060.474
16-1.728-1.171-0.4991.067
17-2.2551.132-1.449-0.582
180.994-1.486-0.191-1.407
190.238-0.035-0.3030.026
Standard thresholds
P-value Threshold
0.001 -0.89369
0.0005 0.72051
0.0001 4.10616