NR6A1.H12INVIVO.0.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NR6A1.H12INVIVO.0.P.C
Gene (human)	NR6A1 (GeneCards)
Gene synonyms (human)	GCNF
Gene (mouse)	Nr6a1
Gene synonyms (mouse)	Gcnf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	14
Consensus	vRRRbYCAAGKbYW
GC content	47.25%
Information content (bits; total / per base)	11.538 / 0.824
Data sources	ChIP-Seq
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (5)	0.792	0.809	0.692	0.718	0.772	0.784	3.176	3.277	177.26	204.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.98	0.981	0.776	0.805	0.626	0.675
Overall, 2 experiments	best	1.0	1.0	0.817	0.843	0.643	0.697
Methyl HT-SELEX, 1 experiments	median	1.0	1.0	0.817	0.843	0.643	0.697
Methyl HT-SELEX, 1 experiments	best	1.0	1.0	0.817	0.843	0.643	0.697
Non-Methyl HT-SELEX, 1 experiments	median	0.961	0.962	0.736	0.767	0.608	0.652
Non-Methyl HT-SELEX, 1 experiments	best	0.961	0.962	0.736	0.767	0.608	0.652

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	GCNF (NR6) {2.1.6} (TFClass)
TF subfamily	{2.1.6.0} (TFClass)
TFClass ID	TFClass: 2.1.6.0.1
HGNC	HGNC:7985
MGI	MGI:1352459
EntrezGene (human)	GeneID:2649 (SSTAR profile)
EntrezGene (mouse)	GeneID:14536 (SSTAR profile)
UniProt ID (human)	NR6A1_HUMAN
UniProt ID (mouse)	NR6A1_MOUSE
UniProt AC (human)	Q15406 (TFClass)
UniProt AC (mouse)	Q64249 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	NR6A1.H12INVIVO.0.P.C.pcm
PWM	NR6A1.H12INVIVO.0.P.C.pwm
PFM	NR6A1.H12INVIVO.0.P.C.pfm
Alignment	NR6A1.H12INVIVO.0.P.C.words.tsv
Threshold to P-value map	NR6A1.H12INVIVO.0.P.C.thr
Motif in other formats
JASPAR format	NR6A1.H12INVIVO.0.P.C_jaspar_format.txt
MEME format	NR6A1.H12INVIVO.0.P.C_meme_format.meme
Transfac format	NR6A1.H12INVIVO.0.P.C_transfac_format.txt
Homer format	NR6A1.H12INVIVO.0.P.C_homer_format_0.001.txt NR6A1.H12INVIVO.0.P.C_homer_format_0.0005.txt NR6A1.H12INVIVO.0.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	211.0	467.0	191.0	128.0
02	594.0	81.0	188.0	134.0
03	608.0	99.0	166.0	124.0
04	181.0	66.0	591.0	159.0
05	57.0	96.0	445.0	399.0
06	31.0	343.0	37.0	586.0
07	10.0	949.0	21.0	17.0
08	965.0	15.0	5.0	12.0
09	891.0	18.0	33.0	55.0
10	67.0	11.0	879.0	40.0
11	31.0	25.0	557.0	384.0
12	56.0	245.0	148.0	548.0
13	32.0	761.0	33.0	171.0
14	773.0	39.0	86.0	99.0

PFM

	A	C	G	T
01	0.212	0.468	0.192	0.128
02	0.596	0.081	0.189	0.134
03	0.61	0.099	0.166	0.124
04	0.182	0.066	0.593	0.159
05	0.057	0.096	0.446	0.4
06	0.031	0.344	0.037	0.588
07	0.01	0.952	0.021	0.017
08	0.968	0.015	0.005	0.012
09	0.894	0.018	0.033	0.055
10	0.067	0.011	0.882	0.04
11	0.031	0.025	0.559	0.385
12	0.056	0.246	0.148	0.55
13	0.032	0.763	0.033	0.172
14	0.775	0.039	0.086	0.099

PWM

	A	C	G	T
01	-0.165	0.625	-0.264	-0.66
02	0.864	-1.11	-0.28	-0.615
03	0.888	-0.913	-0.403	-0.691
04	-0.317	-1.31	0.859	-0.446
05	-1.452	-0.943	0.577	0.468
06	-2.037	0.317	-1.869	0.851
07	-3.064	1.332	-2.402	-2.595
08	1.349	-2.708	-3.619	-2.906
09	1.269	-2.543	-1.978	-1.487
10	-1.295	-2.982	1.255	-1.794
11	-2.037	-2.24	0.8	0.43
12	-1.47	-0.017	-0.517	0.784
13	-2.007	1.112	-1.978	-0.374
14	1.127	-1.818	-1.051	-0.913

Standard thresholds

P-value	Threshold
0.001	4.34671
0.0005	5.26046
0.0001	7.15131