| Motif | NR4A2.H12INVIVO.0.SM.D |
| Gene (human) | NR4A2 (GeneCards) |
| Gene synonyms (human) | NOT, NURR1, TINUR |
| Gene (mouse) | Nr4a2 |
| Gene synonyms (mouse) | Nurr1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | NR4A2.H12INVIVO.0.SM.D |
| Gene (human) | NR4A2 (GeneCards) |
| Gene synonyms (human) | NOT, NURR1, TINUR |
| Gene (mouse) | Nr4a2 |
| Gene synonyms (mouse) | Nurr1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 10 |
| Consensus | nWAAGGTCAn |
| GC content | 42.12% |
| Information content (bits; total / per base) | 11.667 / 1.167 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9649 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.885 | 0.883 | 0.801 | 0.802 | 0.723 | 0.728 |
| best | 0.985 | 0.975 | 0.977 | 0.963 | 0.944 | 0.927 | |
| Methyl HT-SELEX, 1 experiments | median | 0.985 | 0.975 | 0.977 | 0.963 | 0.944 | 0.927 |
| best | 0.985 | 0.975 | 0.977 | 0.963 | 0.944 | 0.927 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.789 | 0.798 | 0.639 | 0.66 | 0.57 | 0.593 |
| best | 0.981 | 0.968 | 0.962 | 0.945 | 0.877 | 0.864 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | NGFI (NR4A) {2.1.4} (TFClass) |
| TF subfamily | {2.1.4.0} (TFClass) |
| TFClass ID | TFClass: 2.1.4.0.2 |
| HGNC | HGNC:7981 |
| MGI | MGI:1352456 |
| EntrezGene (human) | GeneID:4929 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18227 (SSTAR profile) |
| UniProt ID (human) | NR4A2_HUMAN |
| UniProt ID (mouse) | NR4A2_MOUSE |
| UniProt AC (human) | P43354 (TFClass) |
| UniProt AC (mouse) | Q06219 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | NR4A2.H12INVIVO.0.SM.D.pcm |
| PWM | NR4A2.H12INVIVO.0.SM.D.pwm |
| PFM | NR4A2.H12INVIVO.0.SM.D.pfm |
| Alignment | NR4A2.H12INVIVO.0.SM.D.words.tsv |
| Threshold to P-value map | NR4A2.H12INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | NR4A2.H12INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | NR4A2.H12INVIVO.0.SM.D_meme_format.meme |
| Transfac format | NR4A2.H12INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1847.25 | 2150.25 | 2401.25 | 3250.25 |
| 02 | 6208.75 | 109.75 | 1656.75 | 1673.75 |
| 03 | 8764.0 | 10.0 | 113.0 | 762.0 |
| 04 | 9614.0 | 1.0 | 32.0 | 2.0 |
| 05 | 0.0 | 0.0 | 8797.0 | 852.0 |
| 06 | 7.0 | 0.0 | 9641.0 | 1.0 |
| 07 | 21.0 | 172.0 | 575.0 | 8881.0 |
| 08 | 52.0 | 8311.0 | 309.0 | 977.0 |
| 09 | 7783.5 | 134.5 | 1525.5 | 205.5 |
| 10 | 2139.5 | 3063.5 | 1635.5 | 2810.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.191 | 0.223 | 0.249 | 0.337 |
| 02 | 0.643 | 0.011 | 0.172 | 0.173 |
| 03 | 0.908 | 0.001 | 0.012 | 0.079 |
| 04 | 0.996 | 0.0 | 0.003 | 0.0 |
| 05 | 0.0 | 0.0 | 0.912 | 0.088 |
| 06 | 0.001 | 0.0 | 0.999 | 0.0 |
| 07 | 0.002 | 0.018 | 0.06 | 0.92 |
| 08 | 0.005 | 0.861 | 0.032 | 0.101 |
| 09 | 0.807 | 0.014 | 0.158 | 0.021 |
| 10 | 0.222 | 0.317 | 0.169 | 0.291 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.267 | -0.115 | -0.005 | 0.298 |
| 02 | 0.945 | -3.07 | -0.375 | -0.365 |
| 03 | 1.289 | -5.28 | -3.042 | -1.15 |
| 04 | 1.382 | -6.597 | -4.254 | -6.332 |
| 05 | -6.959 | -6.959 | 1.293 | -1.039 |
| 06 | -5.56 | -6.959 | 1.385 | -6.597 |
| 07 | -4.641 | -2.629 | -1.431 | 1.303 |
| 08 | -3.795 | 1.236 | -2.049 | -0.902 |
| 09 | 1.171 | -2.871 | -0.458 | -2.453 |
| 10 | -0.12 | 0.239 | -0.388 | 0.153 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.0545 |
| 0.0005 | 5.24769 |
| 0.0001 | 7.462985 |