MotifNR2F6.H12INVIVO.2.SM.B
Gene (human)NR2F6
(GeneCards)
Gene synonyms (human)EAR2, ERBAL2
Gene (mouse)Nr2f6
Gene synonyms (mouse)Ear-2, Ear2, Erbal2
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length18
ConsensusnvKKKYMWAGGTCAhdvn
GC content51.58%
Information content (bits; total / per base)15.475 / 0.86
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words1485

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.874 0.895 0.788 0.814 0.842 0.871 3.197 3.384 201.444 250.102

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 11 experiments median 0.929 0.909 0.816 0.798 0.68 0.691
best 1.0 0.999 0.995 0.994 0.98 0.973
Methyl HT-SELEX, 3 experiments median 0.997 0.995 0.991 0.987 0.973 0.967
best 1.0 0.999 0.995 0.994 0.976 0.968
Non-Methyl HT-SELEX, 8 experiments median 0.796 0.796 0.671 0.677 0.595 0.609
best 0.998 0.997 0.993 0.99 0.98 0.973
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyRXR-related receptors {2.1.3} (TFClass)
TF subfamilyCOUP (NR2F) {2.1.3.5} (TFClass)
TFClass IDTFClass: 2.1.3.5.3
HGNCHGNC:7977
MGIMGI:1352453
EntrezGene (human)GeneID:2063
(SSTAR profile)
EntrezGene (mouse)GeneID:13864
(SSTAR profile)
UniProt ID (human)NR2F6_HUMAN
UniProt ID (mouse)NR2F6_MOUSE
UniProt AC (human)P10588
(TFClass)
UniProt AC (mouse)P43136
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 8
Methyl-HT-SELEX 3
PCM
ACGT
01482.0273.0476.0254.0
02684.5174.5527.598.5
03130.0131.01085.0139.0
0477.0134.01108.0166.0
0560.0180.0275.0970.0
0679.0974.0145.0287.0
071149.0124.0103.0109.0
081165.012.0149.0159.0
091407.03.073.02.0
100.00.01483.02.0
111.00.01480.04.0
120.011.024.01450.0
134.01334.049.098.0
141195.010.0258.022.0
15440.0331.0196.0518.0
16290.0216.0648.0331.0
17347.5211.5715.5210.5
18365.75337.75535.75245.75
PFM
ACGT
010.3250.1840.3210.171
020.4610.1180.3550.066
030.0880.0880.7310.094
040.0520.090.7460.112
050.040.1210.1850.653
060.0530.6560.0980.193
070.7740.0840.0690.073
080.7850.0080.10.107
090.9470.0020.0490.001
100.00.00.9990.001
110.0010.00.9970.003
120.00.0070.0160.976
130.0030.8980.0330.066
140.8050.0070.1740.015
150.2960.2230.1320.349
160.1950.1450.4360.223
170.2340.1420.4820.142
180.2460.2270.3610.165
PWM
ACGT
010.26-0.3060.247-0.377
020.61-0.7490.35-1.313
03-1.04-1.0331.069-0.974
04-1.555-1.011.09-0.799
05-1.797-0.719-0.2980.957
06-1.5290.962-0.933-0.256
071.126-1.087-1.269-1.214
081.14-3.295-0.906-0.841
091.329-4.348-1.607-4.58
10-5.32-5.321.381-4.58
11-4.883-5.321.379-4.159
12-5.32-3.37-2.671.359
13-4.1591.276-1.993-1.318
141.166-3.451-0.362-2.751
150.169-0.114-0.6340.332
16-0.246-0.5380.555-0.114
17-0.066-0.5590.654-0.564
18-0.015-0.0940.365-0.41
Standard thresholds
P-value Threshold
0.001 2.61551
0.0005 3.88496
0.0001 6.48086