MotifNR2F6.H12CORE.3.SM.B
Gene (human)NR2F6
(GeneCards)
Gene synonyms (human)EAR2, ERBAL2
Gene (mouse)Nr2f6
Gene synonyms (mouse)Ear-2, Ear2, Erbal2
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
B
Motif length16
ConsensushRAGGTCAdhGRYYhn
GC content49.88%
Information content (bits; total / per base)14.871 / 0.929
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2468

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.871 0.879 0.746 0.76 0.832 0.847 2.577 2.691 195.367 217.367

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 11 experiments median 0.958 0.95 0.874 0.853 0.717 0.731
best 1.0 1.0 1.0 0.999 0.997 0.997
Methyl HT-SELEX, 3 experiments median 0.995 0.992 0.988 0.983 0.975 0.965
best 1.0 1.0 1.0 0.999 0.997 0.997
Non-Methyl HT-SELEX, 8 experiments median 0.819 0.813 0.661 0.68 0.579 0.605
best 0.997 0.996 0.994 0.991 0.984 0.978
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyRXR-related receptors {2.1.3} (TFClass)
TF subfamilyCOUP (NR2F) {2.1.3.5} (TFClass)
TFClass IDTFClass: 2.1.3.5.3
HGNCHGNC:7977
MGIMGI:1352453
EntrezGene (human)GeneID:2063
(SSTAR profile)
EntrezGene (mouse)GeneID:13864
(SSTAR profile)
UniProt ID (human)NR2F6_HUMAN
UniProt ID (mouse)NR2F6_MOUSE
UniProt AC (human)P10588
(TFClass)
UniProt AC (mouse)P43136
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 8
Methyl-HT-SELEX 3
PCM
ACGT
011061.75465.75386.75553.75
021695.75100.75459.75211.75
032261.01.0205.01.0
040.00.02468.00.0
051.00.02467.00.0
060.00.04.02464.0
070.02405.09.054.0
082050.02.0414.02.0
091121.0411.0443.0493.0
10664.0527.0281.0996.0
11251.0155.01985.077.0
121390.0191.0753.0134.0
13141.01453.0176.0698.0
14181.01896.0156.0235.0
15542.5484.5295.51145.5
16559.25660.25443.25805.25
PFM
ACGT
010.430.1890.1570.224
020.6870.0410.1860.086
030.9160.00.0830.0
040.00.01.00.0
050.00.01.00.0
060.00.00.0020.998
070.00.9740.0040.022
080.8310.0010.1680.001
090.4540.1670.1790.2
100.2690.2140.1140.404
110.1020.0630.8040.031
120.5630.0770.3050.054
130.0570.5890.0710.283
140.0730.7680.0630.095
150.220.1960.120.464
160.2270.2680.180.326
PWM
ACGT
010.541-0.28-0.465-0.108
021.009-1.796-0.293-1.063
031.296-5.345-1.096-5.345
04-5.759-5.7591.384-5.759
05-5.345-5.7591.384-5.759
06-5.759-5.759-4.6441.382
07-5.7591.358-4.034-2.404
081.199-5.054-0.397-5.054
090.596-0.405-0.33-0.224
100.073-0.157-0.7830.478
11-0.895-1.3721.166-2.059
120.81-1.1660.199-1.516
13-1.4660.855-1.2470.123
14-1.2191.121-1.366-0.96
15-0.128-0.241-0.7330.617
16-0.0980.068-0.3290.266
Standard thresholds
P-value Threshold
0.001 2.17971
0.0005 3.67646
0.0001 6.64861