| Motif | NR2E1.H12RSNP.0.SM.B |
| Gene (human) | NR2E1 (GeneCards) |
| Gene synonyms (human) | TLX |
| Gene (mouse) | Nr2e1 |
| Gene synonyms (mouse) | Tll, Tlx |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | NR2E1.H12RSNP.0.SM.B |
| Gene (human) | NR2E1 (GeneCards) |
| Gene synonyms (human) | TLX |
| Gene (mouse) | Nr2e1 |
| Gene synonyms (mouse) | Tll, Tlx |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 8 |
| Consensus | dAAGTCAh |
| GC content | 34.05% |
| Information content (bits; total / per base) | 12.247 / 1.531 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 7827 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.865 | 0.842 | 0.707 | 0.708 | 0.605 | 0.625 |
| best | 0.979 | 0.965 | 0.962 | 0.942 | 0.903 | 0.881 | |
| Methyl HT-SELEX, 1 experiments | median | 0.979 | 0.965 | 0.961 | 0.942 | 0.892 | 0.873 |
| best | 0.979 | 0.965 | 0.961 | 0.942 | 0.892 | 0.873 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.843 | 0.815 | 0.693 | 0.691 | 0.601 | 0.616 |
| best | 0.977 | 0.961 | 0.962 | 0.941 | 0.903 | 0.881 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.986 | 0.289 | 0.979 | 0.412 |
| batch 2 | 0.749 | 0.319 | 0.79 | 0.575 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | RXR-related receptors {2.1.3} (TFClass) |
| TF subfamily | TLX (NR2E1) {2.1.3.3} (TFClass) |
| TFClass ID | TFClass: 2.1.3.3.1 |
| HGNC | HGNC:7973 |
| MGI | MGI:1100526 |
| EntrezGene (human) | GeneID:7101 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21907 (SSTAR profile) |
| UniProt ID (human) | NR2E1_HUMAN |
| UniProt ID (mouse) | NR2E1_MOUSE |
| UniProt AC (human) | Q9Y466 (TFClass) |
| UniProt AC (mouse) | Q64104 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | NR2E1.H12RSNP.0.SM.B.pcm |
| PWM | NR2E1.H12RSNP.0.SM.B.pwm |
| PFM | NR2E1.H12RSNP.0.SM.B.pfm |
| Alignment | NR2E1.H12RSNP.0.SM.B.words.tsv |
| Threshold to P-value map | NR2E1.H12RSNP.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NR2E1.H12RSNP.0.SM.B_jaspar_format.txt |
| MEME format | NR2E1.H12RSNP.0.SM.B_meme_format.meme |
| Transfac format | NR2E1.H12RSNP.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2946.0 | 916.0 | 1996.0 | 1969.0 |
| 02 | 7827.0 | 0.0 | 0.0 | 0.0 |
| 03 | 7827.0 | 0.0 | 0.0 | 0.0 |
| 04 | 0.0 | 0.0 | 7827.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 7827.0 |
| 06 | 0.0 | 7827.0 | 0.0 | 0.0 |
| 07 | 7827.0 | 0.0 | 0.0 | 0.0 |
| 08 | 3510.25 | 1630.25 | 1125.25 | 1561.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.376 | 0.117 | 0.255 | 0.252 |
| 02 | 1.0 | 0.0 | 0.0 | 0.0 |
| 03 | 1.0 | 0.0 | 0.0 | 0.0 |
| 04 | 0.0 | 0.0 | 1.0 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.0 | 1.0 | 0.0 | 0.0 |
| 07 | 1.0 | 0.0 | 0.0 | 0.0 |
| 08 | 0.448 | 0.208 | 0.144 | 0.199 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.409 | -0.758 | 0.02 | 0.006 |
| 02 | 1.385 | -6.773 | -6.773 | -6.773 |
| 03 | 1.385 | -6.773 | -6.773 | -6.773 |
| 04 | -6.773 | -6.773 | 1.385 | -6.773 |
| 05 | -6.773 | -6.773 | -6.773 | 1.385 |
| 06 | -6.773 | 1.385 | -6.773 | -6.773 |
| 07 | 1.385 | -6.773 | -6.773 | -6.773 |
| 08 | 0.584 | -0.182 | -0.552 | -0.226 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.581615 |
| 0.0005 | 1.264885 |
| 0.0001 | 8.14641 |