MotifNR2E1.H12INVITRO.1.S.B
Gene (human)NR2E1
(GeneCards)
Gene synonyms (human)TLX
Gene (mouse)Nr2e1
Gene synonyms (mouse)Tll, Tlx
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length17
ConsensusvMAGTCAWdAAGTCAhn
GC content34.8%
Information content (bits; total / per base)22.635 / 1.331
Data sourcesHT-SELEX
Aligned words311

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.774 0.767 0.642 0.65 0.571 0.588
best 0.99 0.986 0.944 0.933 0.838 0.831
Methyl HT-SELEX, 1 experiments median 0.99 0.986 0.944 0.933 0.838 0.831
best 0.99 0.986 0.944 0.933 0.838 0.831
Non-Methyl HT-SELEX, 5 experiments median 0.735 0.727 0.621 0.627 0.561 0.575
best 0.982 0.975 0.932 0.916 0.836 0.823

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.9 0.266 0.832 0.475
batch 2 0.671 0.175 0.712 0.494
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyRXR-related receptors {2.1.3} (TFClass)
TF subfamilyTLX (NR2E1) {2.1.3.3} (TFClass)
TFClass IDTFClass: 2.1.3.3.1
HGNCHGNC:7973
MGIMGI:1100526
EntrezGene (human)GeneID:7101
(SSTAR profile)
EntrezGene (mouse)GeneID:21907
(SSTAR profile)
UniProt ID (human)NR2E1_HUMAN
UniProt ID (mouse)NR2E1_MOUSE
UniProt AC (human)Q9Y466
(TFClass)
UniProt AC (mouse)Q64104
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
01120.052.088.051.0
02241.7540.7525.752.75
03275.09.019.08.0
043.00.0308.00.0
050.00.05.0306.0
060.0306.00.05.0
07303.05.03.00.0
08219.028.021.043.0
09109.014.050.0138.0
10303.00.02.06.0
11309.01.01.00.0
120.00.0311.00.0
130.01.00.0310.0
140.0308.00.03.0
15304.00.07.00.0
16160.045.042.064.0
1755.7567.7579.75107.75
PFM
ACGT
010.3860.1670.2830.164
020.7770.1310.0830.009
030.8840.0290.0610.026
040.010.00.990.0
050.00.00.0160.984
060.00.9840.00.016
070.9740.0160.010.0
080.7040.090.0680.138
090.350.0450.1610.444
100.9740.00.0060.019
110.9940.0030.0030.0
120.00.01.00.0
130.00.0030.00.997
140.00.990.00.01
150.9770.00.0230.0
160.5140.1450.1350.206
170.1790.2180.2560.346
PWM
ACGT
010.428-0.3930.122-0.412
021.122-0.63-1.069-2.94
031.25-2.027-1.355-2.127
04-2.882-4.0111.363-4.011
05-4.011-4.011-2.511.356
06-4.0111.356-4.011-2.51
071.347-2.51-2.882-4.011
081.024-0.99-1.261-0.578
090.333-1.635-0.4310.566
101.347-4.011-3.138-2.366
111.366-3.482-3.482-4.011
12-4.011-4.0111.373-4.011
13-4.011-3.482-4.0111.369
14-4.0111.363-4.011-2.882
151.35-4.011-2.239-4.011
160.712-0.534-0.601-0.191
17-0.325-0.1350.0250.321
Standard thresholds
P-value Threshold
0.001 -1.66529
0.0005 -0.05379
0.0001 3.35646