| Motif | NR2E1.H12INVITRO.0.SM.B |
| Gene (human) | NR2E1 (GeneCards) |
| Gene synonyms (human) | TLX |
| Gene (mouse) | Nr2e1 |
| Gene synonyms (mouse) | Tll, Tlx |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | NR2E1.H12INVITRO.0.SM.B |
| Gene (human) | NR2E1 (GeneCards) |
| Gene synonyms (human) | TLX |
| Gene (mouse) | Nr2e1 |
| Gene synonyms (mouse) | Tll, Tlx |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | ddAAGTCAhn |
| GC content | 34.76% |
| Information content (bits; total / per base) | 10.334 / 1.033 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9838 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.875 | 0.853 | 0.715 | 0.716 | 0.61 | 0.63 |
| best | 0.981 | 0.966 | 0.966 | 0.948 | 0.922 | 0.898 | |
| Methyl HT-SELEX, 1 experiments | median | 0.981 | 0.966 | 0.966 | 0.948 | 0.916 | 0.895 |
| best | 0.981 | 0.966 | 0.966 | 0.948 | 0.916 | 0.895 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.851 | 0.823 | 0.698 | 0.696 | 0.6 | 0.617 |
| best | 0.978 | 0.962 | 0.964 | 0.944 | 0.922 | 0.898 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.981 | 0.447 | 0.915 | 0.462 |
| batch 2 | 0.732 | 0.32 | 0.742 | 0.542 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | RXR-related receptors {2.1.3} (TFClass) |
| TF subfamily | TLX (NR2E1) {2.1.3.3} (TFClass) |
| TFClass ID | TFClass: 2.1.3.3.1 |
| HGNC | HGNC:7973 |
| MGI | MGI:1100526 |
| EntrezGene (human) | GeneID:7101 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:21907 (SSTAR profile) |
| UniProt ID (human) | NR2E1_HUMAN |
| UniProt ID (mouse) | NR2E1_MOUSE |
| UniProt AC (human) | Q9Y466 (TFClass) |
| UniProt AC (mouse) | Q64104 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | NR2E1.H12INVITRO.0.SM.B.pcm |
| PWM | NR2E1.H12INVITRO.0.SM.B.pwm |
| PFM | NR2E1.H12INVITRO.0.SM.B.pfm |
| Alignment | NR2E1.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | NR2E1.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NR2E1.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | NR2E1.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | NR2E1.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 4148.25 | 1656.25 | 1830.25 | 2203.25 |
| 02 | 4597.25 | 921.25 | 2165.25 | 2154.25 |
| 03 | 8305.0 | 330.0 | 759.0 | 444.0 |
| 04 | 9168.0 | 216.0 | 325.0 | 129.0 |
| 05 | 3.0 | 0.0 | 9835.0 | 0.0 |
| 06 | 2.0 | 131.0 | 53.0 | 9652.0 |
| 07 | 4.0 | 9202.0 | 53.0 | 579.0 |
| 08 | 9158.0 | 110.0 | 384.0 | 186.0 |
| 09 | 5191.75 | 1459.75 | 996.75 | 2189.75 |
| 10 | 2825.75 | 1974.75 | 1791.75 | 3245.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.422 | 0.168 | 0.186 | 0.224 |
| 02 | 0.467 | 0.094 | 0.22 | 0.219 |
| 03 | 0.844 | 0.034 | 0.077 | 0.045 |
| 04 | 0.932 | 0.022 | 0.033 | 0.013 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.013 | 0.005 | 0.981 |
| 07 | 0.0 | 0.935 | 0.005 | 0.059 |
| 08 | 0.931 | 0.011 | 0.039 | 0.019 |
| 09 | 0.528 | 0.148 | 0.101 | 0.223 |
| 10 | 0.287 | 0.201 | 0.182 | 0.33 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.522 | -0.395 | -0.295 | -0.11 |
| 02 | 0.625 | -0.98 | -0.127 | -0.132 |
| 03 | 1.216 | -2.003 | -1.174 | -1.708 |
| 04 | 1.315 | -2.423 | -2.018 | -2.931 |
| 05 | -6.141 | -6.976 | 1.385 | -6.976 |
| 06 | -6.35 | -2.916 | -3.796 | 1.367 |
| 07 | -5.968 | 1.319 | -3.796 | -1.443 |
| 08 | 1.314 | -3.087 | -1.852 | -2.571 |
| 09 | 0.747 | -0.521 | -0.902 | -0.116 |
| 10 | 0.139 | -0.219 | -0.316 | 0.277 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.664505 |
| 0.0005 | 5.505995 |
| 0.0001 | 7.675825 |