MotifNR1I3.H12INVIVO.2.M.C
Gene (human)NR1I3
(GeneCards)
Gene synonyms (human)CAR
Gene (mouse)Nr1i3
Gene synonyms (mouse)Car
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length20
ConsensusnbWWAGTTCGYnndRvbYhn
GC content42.47%
Information content (bits; total / per base)15.381 / 0.769
Data sourcesMethyl-HT-SELEX
Aligned words706

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (6) 0.676 0.695 0.561 0.581 0.633 0.67 1.669 1.791 67.403 88.004

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.95 0.938 0.819 0.817 0.681 0.702
best 0.966 0.949 0.894 0.875 0.744 0.753
Methyl HT-SELEX, 1 experiments median 0.935 0.926 0.744 0.759 0.618 0.652
best 0.935 0.926 0.744 0.759 0.618 0.652
Non-Methyl HT-SELEX, 1 experiments median 0.966 0.949 0.894 0.875 0.744 0.753
best 0.966 0.949 0.894 0.875 0.744 0.753

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.505 0.085 0.222 0.255
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyVDR (NR1I) {2.1.2.4} (TFClass)
TFClass IDTFClass: 2.1.2.4.3
HGNCHGNC:7969
MGIMGI:1346307
EntrezGene (human)GeneID:9970
(SSTAR profile)
EntrezGene (mouse)GeneID:12355
(SSTAR profile)
UniProt ID (human)NR1I3_HUMAN
UniProt ID (mouse)NR1I3_MOUSE
UniProt AC (human)Q14994
(TFClass)
UniProt AC (mouse)O35627
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01147.25186.25201.25171.25
0282.75263.75149.75209.75
03475.047.084.0100.0
04400.02.0129.0175.0
05705.00.01.00.0
060.00.0706.00.0
070.00.00.0706.0
080.00.00.0706.0
090.0706.00.00.0
10214.02.0490.00.0
1141.0296.042.0327.0
12106.0156.0237.0207.0
13198.0171.0214.0123.0
14379.040.0190.097.0
15488.080.091.047.0
16283.0148.0190.085.0
1765.0126.0163.0352.0
1838.0100.057.0511.0
1976.0245.061.0324.0
20131.0215.0207.0153.0
PFM
ACGT
010.2090.2640.2850.243
020.1170.3740.2120.297
030.6730.0670.1190.142
040.5670.0030.1830.248
050.9990.00.0010.0
060.00.01.00.0
070.00.00.01.0
080.00.00.01.0
090.01.00.00.0
100.3030.0030.6940.0
110.0580.4190.0590.463
120.150.2210.3360.293
130.280.2420.3030.174
140.5370.0570.2690.137
150.6910.1130.1290.067
160.4010.210.2690.12
170.0920.1780.2310.499
180.0540.1420.0810.724
190.1080.3470.0860.459
200.1860.3050.2930.217
PWM
ACGT
01-0.1790.0530.13-0.03
02-0.7470.399-0.1630.171
030.984-1.298-0.732-0.561
040.813-3.891-0.31-0.008
051.378-4.688-4.212-4.688
06-4.688-4.6881.379-4.688
07-4.688-4.688-4.6881.379
08-4.688-4.688-4.6881.379
09-4.6881.379-4.688-4.688
100.191-3.8911.015-4.688
11-1.430.513-1.4070.612
12-0.504-0.1220.2920.158
130.114-0.0310.191-0.357
140.759-1.4540.073-0.591
151.011-0.78-0.654-1.298
160.469-0.1740.073-0.721
17-0.983-0.333-0.0790.686
18-1.503-0.561-1.1111.057
19-0.830.325-1.0450.603
20-0.2950.1960.158-0.141
Standard thresholds
P-value Threshold
0.001 2.02186
0.0005 3.39706
0.0001 6.50926