MotifNR1I3.H12INVITRO.1.PSM.A
Gene (human)NR1I3
(GeneCards)
Gene synonyms (human)CAR
Gene (mouse)Nr1i3
Gene synonyms (mouse)Car
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length17
ConsensusnnWWAGTTCAYbnvvnh
GC content38.48%
Information content (bits; total / per base)14.821 / 0.872
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words395

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 6 (6) 0.677 0.7 0.557 0.584 0.659 0.691 1.729 1.874 77.877 96.638

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.941 0.919 0.83 0.821 0.695 0.711
best 0.978 0.966 0.921 0.905 0.77 0.779
Methyl HT-SELEX, 1 experiments median 0.904 0.873 0.739 0.738 0.619 0.642
best 0.904 0.873 0.739 0.738 0.619 0.642
Non-Methyl HT-SELEX, 1 experiments median 0.978 0.966 0.921 0.905 0.77 0.779
best 0.978 0.966 0.921 0.905 0.77 0.779

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.581 0.11 0.223 0.294
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyVDR (NR1I) {2.1.2.4} (TFClass)
TFClass IDTFClass: 2.1.2.4.3
HGNCHGNC:7969
MGIMGI:1346307
EntrezGene (human)GeneID:9970
(SSTAR profile)
EntrezGene (mouse)GeneID:12355
(SSTAR profile)
UniProt ID (human)NR1I3_HUMAN
UniProt ID (mouse)NR1I3_MOUSE
UniProt AC (human)Q14994
(TFClass)
UniProt AC (mouse)O35627
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 6 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
0174.0116.0104.0101.0
0260.75134.75125.7573.75
03264.019.041.071.0
04285.06.051.053.0
05394.00.01.00.0
060.00.0395.00.0
070.00.00.0395.0
080.00.00.0395.0
090.0395.00.00.0
10392.00.03.00.0
1124.072.014.0285.0
1258.088.0154.095.0
13108.0118.0106.063.0
14200.053.092.050.0
15159.0111.064.061.0
16119.7580.7587.75106.75
1776.577.574.5166.5
PFM
ACGT
010.1870.2940.2630.256
020.1540.3410.3180.187
030.6680.0480.1040.18
040.7220.0150.1290.134
050.9970.00.0030.0
060.00.01.00.0
070.00.00.01.0
080.00.00.01.0
090.01.00.00.0
100.9920.00.0080.0
110.0610.1820.0350.722
120.1470.2230.390.241
130.2730.2990.2680.159
140.5060.1340.2330.127
150.4030.2810.1620.154
160.3030.2040.2220.27
170.1940.1960.1890.422
PWM
ACGT
01-0.2840.1590.0510.022
02-0.4770.3070.238-0.287
030.974-1.587-0.858-0.324
041.05-2.593-0.647-0.61
051.373-4.206-3.693-4.206
06-4.206-4.2061.375-4.206
07-4.206-4.206-4.2061.375
08-4.206-4.206-4.2061.375
09-4.2061.375-4.206-4.206
101.367-4.206-3.105-4.206
11-1.369-0.31-1.8671.05
12-0.522-0.1130.439-0.038
130.0880.1760.07-0.441
140.698-0.61-0.07-0.666
150.4710.115-0.426-0.473
160.19-0.198-0.1160.077
17-0.251-0.238-0.2770.516
Standard thresholds
P-value Threshold
0.001 2.60871
0.0005 3.83541
0.0001 6.67681