MotifNR1I2.H12INVIVO.1.S.D
Gene (human)NR1I2
(GeneCards)
Gene synonyms (human)PXR
Gene (mouse)Nr1i2
Gene synonyms (mouse)Pxr
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length12
ConsensusnbRAGTTCAbdn
GC content47.92%
Information content (bits; total / per base)11.351 / 0.946
Data sourcesHT-SELEX
Aligned words599

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.854 0.813 0.802 0.762 0.721 0.697
best 0.952 0.924 0.905 0.872 0.799 0.781
Methyl HT-SELEX, 1 experiments median 0.952 0.924 0.905 0.872 0.799 0.781
best 0.952 0.924 0.905 0.872 0.799 0.781
Non-Methyl HT-SELEX, 1 experiments median 0.757 0.702 0.699 0.652 0.642 0.613
best 0.757 0.702 0.699 0.652 0.642 0.613
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyVDR (NR1I) {2.1.2.4} (TFClass)
TFClass IDTFClass: 2.1.2.4.2
HGNCHGNC:7968
MGIMGI:1337040
EntrezGene (human)GeneID:8856
(SSTAR profile)
EntrezGene (mouse)GeneID:18171
(SSTAR profile)
UniProt ID (human)NR1I2_HUMAN
UniProt ID (mouse)NR1I2_MOUSE
UniProt AC (human)O75469
(TFClass)
UniProt AC (mouse)O54915
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01116.75109.75230.75141.75
0278.75152.75127.75239.75
03202.026.0359.012.0
04557.05.026.011.0
050.00.0599.00.0
060.00.070.0529.0
070.00.07.0592.0
080.0597.01.01.0
09407.00.0192.00.0
1057.0185.077.0280.0
1184.2575.25256.25183.25
12108.5168.5179.5142.5
PFM
ACGT
010.1950.1830.3850.237
020.1310.2550.2130.4
030.3370.0430.5990.02
040.930.0080.0430.018
050.00.01.00.0
060.00.00.1170.883
070.00.00.0120.988
080.00.9970.0020.002
090.6790.00.3210.0
100.0950.3090.1290.467
110.1410.1260.4280.306
120.1810.2810.30.238
PWM
ACGT
01-0.246-0.3070.429-0.054
02-0.6330.02-0.1570.467
030.297-1.7020.868-2.41
041.306-3.133-1.702-2.486
05-4.55-4.551.378-4.55
06-4.55-4.55-0.7491.254
07-4.55-4.55-2.8681.367
08-4.551.375-4.065-4.065
090.993-4.550.246-4.55
10-0.9490.209-0.6550.621
11-0.567-0.6780.5330.2
12-0.3180.1170.179-0.049
Standard thresholds
P-value Threshold
0.001 4.17666
0.0005 5.396265
0.0001 7.72478