MotifNR1I2.H12INVITRO.0.M.C
Gene (human)NR1I2
(GeneCards)
Gene synonyms (human)PXR
Gene (mouse)Nr1i2
Gene synonyms (mouse)Pxr
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length19
ConsensusnbRAGTTCRhbvRGKKYdn
GC content48.85%
Information content (bits; total / per base)14.419 / 0.759
Data sourcesMethyl-HT-SELEX
Aligned words2483

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.869 0.854 0.803 0.791 0.702 0.703
best 0.998 0.997 0.95 0.946 0.803 0.815
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.95 0.946 0.803 0.815
best 0.998 0.997 0.95 0.946 0.803 0.815
Non-Methyl HT-SELEX, 1 experiments median 0.74 0.712 0.655 0.636 0.601 0.591
best 0.74 0.712 0.655 0.636 0.601 0.591
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyVDR (NR1I) {2.1.2.4} (TFClass)
TFClass IDTFClass: 2.1.2.4.2
HGNCHGNC:7968
MGIMGI:1337040
EntrezGene (human)GeneID:8856
(SSTAR profile)
EntrezGene (mouse)GeneID:18171
(SSTAR profile)
UniProt ID (human)NR1I2_HUMAN
UniProt ID (mouse)NR1I2_MOUSE
UniProt AC (human)O75469
(TFClass)
UniProt AC (mouse)O54915
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01467.25482.25891.25642.25
02323.25617.25460.251082.25
03595.0231.01485.0172.0
042149.012.0315.07.0
0538.04.02441.00.0
063.041.0246.02193.0
0732.06.0373.02072.0
088.02405.012.058.0
091290.016.01169.08.0
10398.0474.0203.01408.0
11291.0380.0599.01213.0
12595.0376.01281.0231.0
131649.0126.0562.0146.0
14146.0140.02038.0159.0
15180.099.0495.01709.0
16162.0145.0527.01649.0
17149.01858.0209.0267.0
181047.25194.251031.25210.25
19493.25703.25396.25890.25
PFM
ACGT
010.1880.1940.3590.259
020.130.2490.1850.436
030.240.0930.5980.069
040.8650.0050.1270.003
050.0150.0020.9830.0
060.0010.0170.0990.883
070.0130.0020.150.834
080.0030.9690.0050.023
090.520.0060.4710.003
100.160.1910.0820.567
110.1170.1530.2410.489
120.240.1510.5160.093
130.6640.0510.2260.059
140.0590.0560.8210.064
150.0720.040.1990.688
160.0650.0580.2120.664
170.060.7480.0840.108
180.4220.0780.4150.085
190.1990.2830.160.359
PWM
ACGT
01-0.283-0.2520.3610.034
02-0.65-0.006-0.2980.555
03-0.042-0.9830.87-1.275
041.24-3.798-0.675-4.242
05-2.746-4.651.367-5.764
06-4.834-2.674-0.9211.26
07-2.909-4.36-0.5071.203
08-4.1361.352-3.798-2.34
090.73-3.5460.632-4.136
10-0.443-0.269-1.1110.817
11-0.754-0.489-0.0360.668
12-0.042-0.4990.723-0.983
130.975-1.582-0.099-1.437
14-1.437-1.4791.187-1.353
15-1.23-1.819-0.2261.011
16-1.334-1.444-0.1630.975
17-1.4171.094-1.082-0.84
180.522-1.1550.506-1.077
19-0.2290.124-0.4470.36
Standard thresholds
P-value Threshold
0.001 3.27811
0.0005 4.41371
0.0001 6.74566