MotifNR1H4.H12INVIVO.1.P.B
Gene (human)NR1H4
(GeneCards)
Gene synonyms (human)BAR, FXR, HRR1, RIP14
Gene (mouse)Nr1h4
Gene synonyms (mouse)Bar, Fxr, Rip14
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusRGKbYRnTGACCYbnddd
GC content55.0%
Information content (bits; total / per base)12.781 / 0.71
Data sourcesChIP-Seq
Aligned words1002

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.941 0.946 0.901 0.91 0.912 0.919 4.039 4.206 300.045 354.796
Mouse 4 (20) 0.833 0.855 0.762 0.81 0.759 0.793 2.778 3.309 329.076 405.678
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.3
HGNCHGNC:7967
MGIMGI:1352464
EntrezGene (human)GeneID:9971
(SSTAR profile)
EntrezGene (mouse)GeneID:20186
(SSTAR profile)
UniProt ID (human)NR1H4_HUMAN
UniProt ID (mouse)NR1H4_MOUSE
UniProt AC (human)Q96RI1
(TFClass)
UniProt AC (mouse)Q60641
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 4 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01606.064.0274.058.0
0268.04.0850.080.0
0372.020.0771.0139.0
0490.0173.0257.0482.0
0527.0732.0104.0139.0
06760.051.0133.058.0
07366.0229.0169.0238.0
0821.020.024.0937.0
0918.040.0940.04.0
10830.070.079.023.0
11190.0798.07.07.0
1274.0903.00.025.0
1335.0382.055.0530.0
14119.0433.0137.0313.0
15220.0141.0293.0348.0
16285.0159.0397.0161.0
17174.0136.0457.0235.0
18189.0165.0452.0196.0
PFM
ACGT
010.6050.0640.2730.058
020.0680.0040.8480.08
030.0720.020.7690.139
040.090.1730.2560.481
050.0270.7310.1040.139
060.7580.0510.1330.058
070.3650.2290.1690.238
080.0210.020.0240.935
090.0180.040.9380.004
100.8280.070.0790.023
110.190.7960.0070.007
120.0740.9010.00.025
130.0350.3810.0550.529
140.1190.4320.1370.312
150.220.1410.2920.347
160.2840.1590.3960.161
170.1740.1360.4560.235
180.1890.1650.4510.196
PWM
ACGT
010.879-1.3450.089-1.441
02-1.286-3.7851.217-1.127
03-1.23-2.4521.12-0.584
04-1.012-0.3670.0250.651
05-2.1721.068-0.869-0.584
061.105-1.565-0.627-1.441
070.377-0.089-0.39-0.051
08-2.407-2.452-2.2831.314
09-2.548-1.7991.317-3.785
101.193-1.257-1.139-2.322
11-0.2741.154-3.364-3.364
12-1.2031.277-4.984-2.245
13-1.9270.42-1.4920.746
14-0.7370.544-0.5980.221
15-0.129-0.5690.1560.327
160.128-0.4510.458-0.438
17-0.361-0.6050.598-0.063
18-0.279-0.4140.587-0.243
Standard thresholds
P-value Threshold
0.001 4.00836
0.0005 4.97866
0.0001 7.00376