MotifNR1H4.H12INVITRO.2.P.D
Gene (human)NR1H4
(GeneCards)
Gene synonyms (human)BAR, FXR, HRR1, RIP14
Gene (mouse)Nr1h4
Gene synonyms (mouse)Bar, Fxr, Rip14
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
D
Motif length7
ConsensusRvTGACC
GC content56.27%
Information content (bits; total / per base)8.003 / 1.143
Data sourcesChIP-Seq
Aligned words971

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.823 0.836 0.691 0.7 0.737 0.748 1.784 1.821 123.148 140.699
Mouse 4 (20) 0.746 0.764 0.608 0.634 0.648 0.675 1.477 1.591 142.653 173.824
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.3
HGNCHGNC:7967
MGIMGI:1352464
EntrezGene (human)GeneID:9971
(SSTAR profile)
EntrezGene (mouse)GeneID:20186
(SSTAR profile)
UniProt ID (human)NR1H4_HUMAN
UniProt ID (mouse)NR1H4_MOUSE
UniProt AC (human)Q96RI1
(TFClass)
UniProt AC (mouse)Q60641
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 4 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01583.0118.0219.051.0
02262.0376.0224.0109.0
0313.017.03.0938.0
0413.020.0937.01.0
05783.041.0124.023.0
0697.0864.08.02.0
0773.0872.02.024.0
PFM
ACGT
010.60.1220.2260.053
020.270.3870.2310.112
030.0130.0180.0030.966
040.0130.0210.9650.001
050.8060.0420.1280.024
060.10.890.0080.002
070.0750.8980.0020.025
PWM
ACGT
010.872-0.714-0.102-1.534
020.0760.435-0.08-0.792
03-2.81-2.57-3.9471.346
04-2.81-2.4211.345-4.499
051.166-1.744-0.665-2.291
06-0.9071.264-3.225-4.185
07-1.1851.274-4.185-2.252
Standard thresholds
P-value Threshold
0.001 5.21512
0.0005 5.833365
0.0001 7.29239