MotifNR1H4.H12INVITRO.0.P.D
Gene (human)NR1H4
(GeneCards)
Gene synonyms (human)BAR, FXR, HRR1, RIP14
Gene (mouse)Nr1h4
Gene synonyms (mouse)Bar, Fxr, Rip14
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length20
ConsensusRGKKSAvYGvCCbbvvKKnY
GC content62.34%
Information content (bits; total / per base)12.93 / 0.646
Data sourcesChIP-Seq
Aligned words918

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.928 0.932 0.875 0.888 0.879 0.888 3.724 3.827 303.882 357.638
Mouse 4 (20) 0.887 0.913 0.854 0.872 0.859 0.887 3.766 4.0 509.934 634.886
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.3
HGNCHGNC:7967
MGIMGI:1352464
EntrezGene (human)GeneID:9971
(SSTAR profile)
EntrezGene (mouse)GeneID:20186
(SSTAR profile)
UniProt ID (human)NR1H4_HUMAN
UniProt ID (mouse)NR1H4_MOUSE
UniProt AC (human)Q96RI1
(TFClass)
UniProt AC (mouse)Q60641
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 4 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01478.019.0394.027.0
0278.012.0788.040.0
0377.019.0690.0132.0
0430.072.0262.0554.0
0516.0674.0136.092.0
06735.054.0102.027.0
07357.0224.0211.0126.0
0838.0128.060.0692.0
0965.034.0816.03.0
10497.0105.0222.094.0
1170.0790.029.029.0
1284.0758.04.072.0
1349.0347.0224.0298.0
14171.0372.0185.0190.0
15179.0208.0368.0163.0
16298.0227.0315.078.0
1792.030.0676.0120.0
1873.070.0649.0126.0
19135.0209.0258.0316.0
2047.0613.092.0166.0
PFM
ACGT
010.5210.0210.4290.029
020.0850.0130.8580.044
030.0840.0210.7520.144
040.0330.0780.2850.603
050.0170.7340.1480.1
060.8010.0590.1110.029
070.3890.2440.230.137
080.0410.1390.0650.754
090.0710.0370.8890.003
100.5410.1140.2420.102
110.0760.8610.0320.032
120.0920.8260.0040.078
130.0530.3780.2440.325
140.1860.4050.2020.207
150.1950.2270.4010.178
160.3250.2470.3430.085
170.10.0330.7360.131
180.080.0760.7070.137
190.1470.2280.2810.344
200.0510.6680.10.181
PWM
ACGT
010.73-2.4130.537-2.086
02-1.065-2.8261.228-1.713
03-1.078-2.4131.096-0.548
04-1.987-1.1430.1320.877
05-2.5691.072-0.518-0.903
061.159-1.423-0.802-2.086
070.439-0.024-0.083-0.594
08-1.762-0.578-1.3211.099
09-1.243-1.8681.263-3.895
100.769-0.773-0.033-0.882
11-1.1711.231-2.019-2.019
12-0.9921.19-3.702-1.143
13-1.5170.411-0.0240.259
14-0.2920.48-0.214-0.187
15-0.246-0.0980.469-0.339
160.259-0.0110.315-1.065
17-0.903-1.9871.075-0.642
18-1.13-1.1711.035-0.594
19-0.525-0.0930.1160.318
20-1.5580.978-0.903-0.321
Standard thresholds
P-value Threshold
0.001 4.03271
0.0005 4.96351
0.0001 6.92986