MotifNR1H3.H12INVIVO.1.P.B
Gene (human)NR1H3
(GeneCards)
Gene synonyms (human)LXRA
Gene (mouse)Nr1h3
Gene synonyms (mouse)Lxra
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length13
ConsensusbbhRRGGTCAbhv
GC content51.15%
Information content (bits; total / per base)9.616 / 0.74
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (20) 0.702 0.766 0.541 0.592 0.679 0.743 1.752 2.033 34.213 75.62
Mouse 8 (49) 0.716 0.825 0.578 0.68 0.677 0.79 1.844 2.337 57.854 124.959
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.1
HGNCHGNC:7966
MGIMGI:1352462
EntrezGene (human)GeneID:10062
(SSTAR profile)
EntrezGene (mouse)GeneID:22259
(SSTAR profile)
UniProt ID (human)NR1H3_HUMAN
UniProt ID (mouse)NR1H3_MOUSE
UniProt AC (human)Q13133
(TFClass)
UniProt AC (mouse)Q9Z0Y9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 8 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01164.0411.0166.0259.0
02126.0413.0161.0300.0
03462.0200.067.0271.0
04323.073.0549.055.0
05695.010.0286.09.0
068.03.0979.010.0
074.05.0844.0147.0
0826.050.072.0852.0
0920.0771.011.0198.0
10974.011.02.013.0
11140.0498.0153.0209.0
12261.0161.0147.0431.0
13222.0195.0411.0172.0
PFM
ACGT
010.1640.4110.1660.259
020.1260.4130.1610.3
030.4620.20.0670.271
040.3230.0730.5490.055
050.6950.010.2860.009
060.0080.0030.9790.01
070.0040.0050.8440.147
080.0260.050.0720.852
090.020.7710.0110.198
100.9740.0110.0020.013
110.140.4980.1530.209
120.2610.1610.1470.431
130.2220.1950.4110.172
PWM
ACGT
01-0.4180.494-0.4060.035
02-0.6780.499-0.4360.181
030.611-0.221-1.2980.08
040.255-1.2150.783-1.49
051.018-3.0660.134-3.156
06-3.253-3.9751.36-3.066
07-3.783-3.6221.212-0.526
08-2.206-1.582-1.2281.221
09-2.451.122-2.985-0.231
101.355-2.985-4.213-2.839
11-0.5740.686-0.487-0.178
120.043-0.436-0.5260.542
13-0.118-0.2470.494-0.371
Standard thresholds
P-value Threshold
0.001 4.87431
0.0005 5.73891
0.0001 7.390565