| Motif | NR1H3.H12INVITRO.1.P.D |
| Gene (human) | NR1H3 (GeneCards) |
| Gene synonyms (human) | LXRA |
| Gene (mouse) | Nr1h3 |
| Gene synonyms (mouse) | Lxra |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | D |
| Motif | NR1H3.H12INVITRO.1.P.D |
| Gene (human) | NR1H3 (GeneCards) |
| Gene synonyms (human) | LXRA |
| Gene (mouse) | Nr1h3 |
| Gene synonyms (mouse) | Lxra |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | D |
| Motif length | 13 |
| Consensus | bbhRRGGTCAbhv |
| GC content | 51.15% |
| Information content (bits; total / per base) | 9.616 / 0.74 |
| Data sources | ChIP-Seq |
| Aligned words | 1000 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 3 (20) | 0.702 | 0.766 | 0.541 | 0.592 | 0.679 | 0.743 | 1.752 | 2.033 | 34.213 | 75.62 |
| Mouse | 8 (49) | 0.716 | 0.825 | 0.578 | 0.68 | 0.677 | 0.79 | 1.844 | 2.337 | 57.854 | 124.959 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Thyroid hormone receptor-related {2.1.2} (TFClass) |
| TF subfamily | LXR (NR1H) {2.1.2.7} (TFClass) |
| TFClass ID | TFClass: 2.1.2.7.1 |
| HGNC | HGNC:7966 |
| MGI | MGI:1352462 |
| EntrezGene (human) | GeneID:10062 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:22259 (SSTAR profile) |
| UniProt ID (human) | NR1H3_HUMAN |
| UniProt ID (mouse) | NR1H3_MOUSE |
| UniProt AC (human) | Q13133 (TFClass) |
| UniProt AC (mouse) | Q9Z0Y9 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 3 human, 8 mouse |
| HT-SELEX | 0 |
| Methyl-HT-SELEX | 0 |
| PCM | NR1H3.H12INVITRO.1.P.D.pcm |
| PWM | NR1H3.H12INVITRO.1.P.D.pwm |
| PFM | NR1H3.H12INVITRO.1.P.D.pfm |
| Alignment | NR1H3.H12INVITRO.1.P.D.words.tsv |
| Threshold to P-value map | NR1H3.H12INVITRO.1.P.D.thr |
| Motif in other formats | |
| JASPAR format | NR1H3.H12INVITRO.1.P.D_jaspar_format.txt |
| MEME format | NR1H3.H12INVITRO.1.P.D_meme_format.meme |
| Transfac format | NR1H3.H12INVITRO.1.P.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 164.0 | 411.0 | 166.0 | 259.0 |
| 02 | 126.0 | 413.0 | 161.0 | 300.0 |
| 03 | 462.0 | 200.0 | 67.0 | 271.0 |
| 04 | 323.0 | 73.0 | 549.0 | 55.0 |
| 05 | 695.0 | 10.0 | 286.0 | 9.0 |
| 06 | 8.0 | 3.0 | 979.0 | 10.0 |
| 07 | 4.0 | 5.0 | 844.0 | 147.0 |
| 08 | 26.0 | 50.0 | 72.0 | 852.0 |
| 09 | 20.0 | 771.0 | 11.0 | 198.0 |
| 10 | 974.0 | 11.0 | 2.0 | 13.0 |
| 11 | 140.0 | 498.0 | 153.0 | 209.0 |
| 12 | 261.0 | 161.0 | 147.0 | 431.0 |
| 13 | 222.0 | 195.0 | 411.0 | 172.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.164 | 0.411 | 0.166 | 0.259 |
| 02 | 0.126 | 0.413 | 0.161 | 0.3 |
| 03 | 0.462 | 0.2 | 0.067 | 0.271 |
| 04 | 0.323 | 0.073 | 0.549 | 0.055 |
| 05 | 0.695 | 0.01 | 0.286 | 0.009 |
| 06 | 0.008 | 0.003 | 0.979 | 0.01 |
| 07 | 0.004 | 0.005 | 0.844 | 0.147 |
| 08 | 0.026 | 0.05 | 0.072 | 0.852 |
| 09 | 0.02 | 0.771 | 0.011 | 0.198 |
| 10 | 0.974 | 0.011 | 0.002 | 0.013 |
| 11 | 0.14 | 0.498 | 0.153 | 0.209 |
| 12 | 0.261 | 0.161 | 0.147 | 0.431 |
| 13 | 0.222 | 0.195 | 0.411 | 0.172 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.418 | 0.494 | -0.406 | 0.035 |
| 02 | -0.678 | 0.499 | -0.436 | 0.181 |
| 03 | 0.611 | -0.221 | -1.298 | 0.08 |
| 04 | 0.255 | -1.215 | 0.783 | -1.49 |
| 05 | 1.018 | -3.066 | 0.134 | -3.156 |
| 06 | -3.253 | -3.975 | 1.36 | -3.066 |
| 07 | -3.783 | -3.622 | 1.212 | -0.526 |
| 08 | -2.206 | -1.582 | -1.228 | 1.221 |
| 09 | -2.45 | 1.122 | -2.985 | -0.231 |
| 10 | 1.355 | -2.985 | -4.213 | -2.839 |
| 11 | -0.574 | 0.686 | -0.487 | -0.178 |
| 12 | 0.043 | -0.436 | -0.526 | 0.542 |
| 13 | -0.118 | -0.247 | 0.494 | -0.371 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.87431 |
| 0.0005 | 5.73891 |
| 0.0001 | 7.390565 |