MotifNR1H3.H12INVITRO.0.P.D
Gene (human)NR1H3
(GeneCards)
Gene synonyms (human)LXRA
Gene (mouse)Nr1h3
Gene synonyms (mouse)Lxra
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length17
ConsensusvRGGKhAYhnnRGGKCA
GC content51.92%
Information content (bits; total / per base)12.74 / 0.749
Data sourcesChIP-Seq
Aligned words999

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (20) 0.73 0.82 0.651 0.739 0.719 0.81 2.814 3.459 60.328 125.921
Mouse 8 (49) 0.761 0.877 0.693 0.835 0.727 0.87 2.716 4.254 79.796 184.31
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.1
HGNCHGNC:7966
MGIMGI:1352462
EntrezGene (human)GeneID:10062
(SSTAR profile)
EntrezGene (mouse)GeneID:22259
(SSTAR profile)
UniProt ID (human)NR1H3_HUMAN
UniProt ID (mouse)NR1H3_MOUSE
UniProt AC (human)Q13133
(TFClass)
UniProt AC (mouse)Q9Z0Y9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 8 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01299.0141.0464.095.0
02505.029.0444.021.0
0388.05.0836.070.0
0413.013.0820.0153.0
0528.0118.0135.0718.0
06136.0392.053.0418.0
07862.023.045.069.0
0881.0656.039.0223.0
09107.0262.096.0534.0
10302.0261.0184.0252.0
11223.0219.0334.0223.0
12650.085.0215.049.0
1359.07.0901.032.0
1424.013.0768.0194.0
15117.0110.0168.0604.0
1617.0867.021.094.0
17882.020.073.024.0
PFM
ACGT
010.2990.1410.4640.095
020.5060.0290.4440.021
030.0880.0050.8370.07
040.0130.0130.8210.153
050.0280.1180.1350.719
060.1360.3920.0530.418
070.8630.0230.0450.069
080.0810.6570.0390.223
090.1070.2620.0960.535
100.3020.2610.1840.252
110.2230.2190.3340.223
120.6510.0850.2150.049
130.0590.0070.9020.032
140.0240.0130.7690.194
150.1170.110.1680.605
160.0170.8680.0210.094
170.8830.020.0730.024
PWM
ACGT
010.179-0.5660.616-0.955
020.701-2.1020.572-2.404
03-1.031-3.6211.203-1.254
04-2.838-2.8381.184-0.486
05-2.135-0.742-0.6091.052
06-0.6020.448-1.5250.512
071.234-2.319-1.683-1.269
08-1.1120.961-1.82-0.112
09-0.8390.048-0.9450.756
100.1890.044-0.3030.009
11-0.112-0.130.289-0.112
120.952-1.065-0.149-1.601
13-1.421-3.3611.278-2.009
14-2.28-2.8381.119-0.251
15-0.751-0.811-0.3930.879
16-2.5971.24-2.404-0.966
171.257-2.449-1.214-2.28
Standard thresholds
P-value Threshold
0.001 4.03506
0.0005 4.98696
0.0001 6.98411