MotifNR1H2.H12INVIVO.0.P.C
Gene (human)NR1H2
(GeneCards)
Gene synonyms (human)LXRB, NER, UNR
Gene (mouse)Nr1h2
Gene synonyms (mouse)Lxrb, Rip15, Unr, Unr2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length18
ConsensusnnnnhRAGGTCAhhdnvv
GC content52.21%
Information content (bits; total / per base)11.057 / 0.614
Data sourcesChIP-Seq
Aligned words992

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.9 0.905 0.799 0.807 0.871 0.878 2.985 3.077 152.638 180.824
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.2
HGNCHGNC:7965
MGIMGI:1352463
EntrezGene (human)GeneID:7376
(SSTAR profile)
EntrezGene (mouse)GeneID:22260
(SSTAR profile)
UniProt ID (human)NR1H2_HUMAN
UniProt ID (mouse)NR1H2_MOUSE
UniProt AC (human)P55055
(TFClass)
UniProt AC (mouse)Q60644
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01252.0225.0243.0272.0
02315.0207.0291.0179.0
03202.0332.0205.0253.0
04177.0364.0186.0265.0
05436.0197.0113.0246.0
06317.068.0560.047.0
07683.02.0304.03.0
0814.01.0973.04.0
093.03.0958.028.0
106.013.041.0932.0
1123.0782.010.0177.0
12986.01.01.04.0
13177.0476.091.0248.0
14196.0194.0140.0462.0
15236.0177.0401.0178.0
16291.0259.0250.0192.0
17390.0256.0231.0115.0
18126.0239.0529.098.0
PFM
ACGT
010.2540.2270.2450.274
020.3180.2090.2930.18
030.2040.3350.2070.255
040.1780.3670.1880.267
050.440.1990.1140.248
060.320.0690.5650.047
070.6890.0020.3060.003
080.0140.0010.9810.004
090.0030.0030.9660.028
100.0060.0130.0410.94
110.0230.7880.010.178
120.9940.0010.0010.004
130.1780.480.0920.25
140.1980.1960.1410.466
150.2380.1780.4040.179
160.2930.2610.2520.194
170.3930.2580.2330.116
180.1270.2410.5330.099
PWM
ACGT
010.016-0.097-0.020.092
020.238-0.1790.159-0.323
03-0.2040.29-0.1890.02
04-0.3350.382-0.2850.066
050.561-0.228-0.778-0.008
060.244-1.2760.811-1.634
071.009-4.2050.202-3.968
08-2.765-4.5181.362-3.776
09-3.968-3.9681.346-2.128
10-3.476-2.831-1.7661.319
11-2.3131.144-3.059-0.335
121.375-4.518-4.518-3.776
13-0.3350.649-0.9910.0
14-0.233-0.244-0.5660.619
15-0.049-0.3350.478-0.329
160.1590.0430.008-0.254
170.450.032-0.071-0.761
18-0.67-0.0370.754-0.918
Standard thresholds
P-value Threshold
0.001 4.39791
0.0005 5.46346
0.0001 7.50781