MotifNR1H2.H12INVITRO.1.P.D
Gene (human)NR1H2
(GeneCards)
Gene synonyms (human)LXRB, NER, UNR
Gene (mouse)Nr1h2
Gene synonyms (mouse)Lxrb, Rip15, Unr, Unr2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length19
ConsensusbhvRGGTYAYhnnvSKbYR
GC content52.47%
Information content (bits; total / per base)12.062 / 0.635
Data sourcesChIP-Seq
Aligned words992

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (7) 0.891 0.897 0.83 0.843 0.853 0.863 4.029 4.204 159.959 175.959
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyLXR (NR1H) {2.1.2.7} (TFClass)
TFClass IDTFClass: 2.1.2.7.2
HGNCHGNC:7965
MGIMGI:1352463
EntrezGene (human)GeneID:7376
(SSTAR profile)
EntrezGene (mouse)GeneID:22260
(SSTAR profile)
UniProt ID (human)NR1H2_HUMAN
UniProt ID (mouse)NR1H2_MOUSE
UniProt AC (human)P55055
(TFClass)
UniProt AC (mouse)Q60644
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01178.0396.0228.0190.0
02395.0226.0139.0232.0
03286.097.0529.080.0
04547.07.0429.09.0
0543.02.0907.040.0
0614.010.0870.098.0
0724.063.070.0835.0
0872.0574.034.0312.0
09920.09.025.038.0
10111.0568.052.0261.0
11135.0221.091.0545.0
12255.0216.0293.0228.0
13285.0222.0316.0169.0
14553.0166.0221.052.0
1575.0126.0745.046.0
1645.076.0648.0223.0
17110.0155.0173.0554.0
1875.0739.066.0112.0
19730.084.096.082.0
PFM
ACGT
010.1790.3990.230.192
020.3980.2280.140.234
030.2880.0980.5330.081
040.5510.0070.4320.009
050.0430.0020.9140.04
060.0140.010.8770.099
070.0240.0640.0710.842
080.0730.5790.0340.315
090.9270.0090.0250.038
100.1120.5730.0520.263
110.1360.2230.0920.549
120.2570.2180.2950.23
130.2870.2240.3190.17
140.5570.1670.2230.052
150.0760.1270.7510.046
160.0450.0770.6530.225
170.1110.1560.1740.558
180.0760.7450.0670.113
190.7360.0850.0970.083
PWM
ACGT
01-0.3290.465-0.083-0.264
020.463-0.092-0.574-0.066
030.142-0.9280.754-1.117
040.787-3.3540.545-3.148
05-1.72-4.2051.292-1.789
06-2.765-3.0591.25-0.918
07-2.273-1.35-1.2481.209
08-1.220.835-1.9450.228
091.306-3.148-2.235-1.838
10-0.7950.825-1.5360.051
11-0.602-0.114-0.9910.784
120.028-0.1370.166-0.083
130.138-0.110.241-0.38
140.798-0.398-0.114-1.536
15-1.18-0.671.095-1.655
16-1.676-1.1670.956-0.105
17-0.804-0.466-0.3570.8
18-1.181.087-1.305-0.787
191.075-1.069-0.938-1.093
Standard thresholds
P-value Threshold
0.001 4.24391
0.0005 5.15296
0.0001 7.05516