| Motif | NR1D2.H12INVIVO.1.SM.B |
| Gene (human) | NR1D2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nr1d2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | NR1D2.H12INVIVO.1.SM.B |
| Gene (human) | NR1D2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nr1d2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 26 |
| Consensus | nvRRKhAKTAGGTCAGTRGGKYRvbn |
| GC content | 51.57% |
| Information content (bits; total / per base) | 25.352 / 0.975 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 752 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 2 (12) | 0.745 | 0.798 | 0.637 | 0.71 | 0.705 | 0.756 | 2.661 | 3.034 | 82.098 | 128.328 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.999 | 0.998 | 0.943 | 0.942 | 0.785 | 0.803 |
| best | 0.999 | 0.999 | 0.953 | 0.949 | 0.798 | 0.814 | |
| Methyl HT-SELEX, 1 experiments | median | 0.999 | 0.999 | 0.934 | 0.934 | 0.772 | 0.793 |
| best | 0.999 | 0.999 | 0.934 | 0.934 | 0.772 | 0.793 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 0.998 | 0.998 | 0.953 | 0.949 | 0.798 | 0.814 |
| best | 0.998 | 0.998 | 0.953 | 0.949 | 0.798 | 0.814 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Thyroid hormone receptor-related {2.1.2} (TFClass) |
| TF subfamily | REVERBA (NR1D) {2.1.2.3} (TFClass) |
| TFClass ID | TFClass: 2.1.2.3.2 |
| HGNC | HGNC:7963 |
| MGI | MGI:2449205 |
| EntrezGene (human) | GeneID:9975 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:353187 (SSTAR profile) |
| UniProt ID (human) | NR1D2_HUMAN |
| UniProt ID (mouse) | NR1D2_MOUSE |
| UniProt AC (human) | Q14995 (TFClass) |
| UniProt AC (mouse) | Q60674 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 2 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | NR1D2.H12INVIVO.1.SM.B.pcm |
| PWM | NR1D2.H12INVIVO.1.SM.B.pwm |
| PFM | NR1D2.H12INVIVO.1.SM.B.pfm |
| Alignment | NR1D2.H12INVIVO.1.SM.B.words.tsv |
| Threshold to P-value map | NR1D2.H12INVIVO.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NR1D2.H12INVIVO.1.SM.B_jaspar_format.txt |
| MEME format | NR1D2.H12INVIVO.1.SM.B_meme_format.meme |
| Transfac format | NR1D2.H12INVIVO.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 146.0 | 127.0 | 229.0 | 250.0 |
| 02 | 362.0 | 89.0 | 213.0 | 88.0 |
| 03 | 93.0 | 79.0 | 494.0 | 86.0 |
| 04 | 91.0 | 66.0 | 521.0 | 74.0 |
| 05 | 105.0 | 36.0 | 130.0 | 481.0 |
| 06 | 237.0 | 308.0 | 28.0 | 179.0 |
| 07 | 588.0 | 0.0 | 10.0 | 154.0 |
| 08 | 68.0 | 48.0 | 565.0 | 71.0 |
| 09 | 3.0 | 8.0 | 15.0 | 726.0 |
| 10 | 466.0 | 0.0 | 286.0 | 0.0 |
| 11 | 1.0 | 0.0 | 747.0 | 4.0 |
| 12 | 0.0 | 0.0 | 752.0 | 0.0 |
| 13 | 0.0 | 1.0 | 9.0 | 742.0 |
| 14 | 1.0 | 633.0 | 0.0 | 118.0 |
| 15 | 745.0 | 0.0 | 7.0 | 0.0 |
| 16 | 38.0 | 43.0 | 653.0 | 18.0 |
| 17 | 14.0 | 23.0 | 32.0 | 683.0 |
| 18 | 415.0 | 11.0 | 296.0 | 30.0 |
| 19 | 25.0 | 21.0 | 679.0 | 27.0 |
| 20 | 21.0 | 25.0 | 681.0 | 25.0 |
| 21 | 27.0 | 33.0 | 98.0 | 594.0 |
| 22 | 27.0 | 597.0 | 52.0 | 76.0 |
| 23 | 531.0 | 25.0 | 171.0 | 25.0 |
| 24 | 195.0 | 136.0 | 305.0 | 116.0 |
| 25 | 112.25 | 137.25 | 241.25 | 261.25 |
| 26 | 162.75 | 131.75 | 289.75 | 167.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.194 | 0.169 | 0.305 | 0.332 |
| 02 | 0.481 | 0.118 | 0.283 | 0.117 |
| 03 | 0.124 | 0.105 | 0.657 | 0.114 |
| 04 | 0.121 | 0.088 | 0.693 | 0.098 |
| 05 | 0.14 | 0.048 | 0.173 | 0.64 |
| 06 | 0.315 | 0.41 | 0.037 | 0.238 |
| 07 | 0.782 | 0.0 | 0.013 | 0.205 |
| 08 | 0.09 | 0.064 | 0.751 | 0.094 |
| 09 | 0.004 | 0.011 | 0.02 | 0.965 |
| 10 | 0.62 | 0.0 | 0.38 | 0.0 |
| 11 | 0.001 | 0.0 | 0.993 | 0.005 |
| 12 | 0.0 | 0.0 | 1.0 | 0.0 |
| 13 | 0.0 | 0.001 | 0.012 | 0.987 |
| 14 | 0.001 | 0.842 | 0.0 | 0.157 |
| 15 | 0.991 | 0.0 | 0.009 | 0.0 |
| 16 | 0.051 | 0.057 | 0.868 | 0.024 |
| 17 | 0.019 | 0.031 | 0.043 | 0.908 |
| 18 | 0.552 | 0.015 | 0.394 | 0.04 |
| 19 | 0.033 | 0.028 | 0.903 | 0.036 |
| 20 | 0.028 | 0.033 | 0.906 | 0.033 |
| 21 | 0.036 | 0.044 | 0.13 | 0.79 |
| 22 | 0.036 | 0.794 | 0.069 | 0.101 |
| 23 | 0.706 | 0.033 | 0.227 | 0.033 |
| 24 | 0.259 | 0.181 | 0.406 | 0.154 |
| 25 | 0.149 | 0.183 | 0.321 | 0.347 |
| 26 | 0.216 | 0.175 | 0.385 | 0.223 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.25 | -0.388 | 0.196 | 0.283 |
| 02 | 0.651 | -0.738 | 0.124 | -0.749 |
| 03 | -0.695 | -0.855 | 0.961 | -0.772 |
| 04 | -0.716 | -1.031 | 1.014 | -0.919 |
| 05 | -0.576 | -1.617 | -0.365 | 0.934 |
| 06 | 0.23 | 0.49 | -1.856 | -0.049 |
| 07 | 1.134 | -4.741 | -2.789 | -0.198 |
| 08 | -1.002 | -1.34 | 1.095 | -0.959 |
| 09 | -3.707 | -2.978 | -2.432 | 1.345 |
| 10 | 0.903 | -4.741 | 0.417 | -4.741 |
| 11 | -4.269 | -4.741 | 1.373 | -3.513 |
| 12 | -4.741 | -4.741 | 1.38 | -4.741 |
| 13 | -4.741 | -4.269 | -2.879 | 1.366 |
| 14 | -4.269 | 1.208 | -4.741 | -0.461 |
| 15 | 1.37 | -4.741 | -3.087 | -4.741 |
| 16 | -1.565 | -1.446 | 1.239 | -2.267 |
| 17 | -2.494 | -2.04 | -1.729 | 1.284 |
| 18 | 0.787 | -2.707 | 0.451 | -1.79 |
| 19 | -1.962 | -2.125 | 1.278 | -1.89 |
| 20 | -2.125 | -1.962 | 1.281 | -1.962 |
| 21 | -1.89 | -1.7 | -0.643 | 1.144 |
| 22 | -1.89 | 1.149 | -1.263 | -0.893 |
| 23 | 1.033 | -1.962 | -0.094 | -1.962 |
| 24 | 0.036 | -0.32 | 0.481 | -0.477 |
| 25 | -0.51 | -0.311 | 0.247 | 0.327 |
| 26 | -0.143 | -0.352 | 0.43 | -0.113 |
| P-value | Threshold |
|---|---|
| 0.001 | -2.87359 |
| 0.0005 | -1.20679 |
| 0.0001 | 2.33131 |