MotifNR1D1.H12INVIVO.1.SM.B
Gene (human)NR1D1
(GeneCards)
Gene synonyms (human)EAR1, HREV, THRAL
Gene (mouse)Nr1d1
Gene synonyms (mouse)Ear1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length18
ConsensusWnYRGGTCASTRGGTCAn
GC content50.03%
Information content (bits; total / per base)22.393 / 1.244
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8005

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 10 (64) 0.706 0.807 0.635 0.747 0.672 0.79 2.709 4.082 70.327 167.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.865 0.875 0.691 0.713 0.604 0.628
best 0.947 0.951 0.746 0.767 0.638 0.664
Methyl HT-SELEX, 1 experiments median 0.947 0.951 0.746 0.767 0.638 0.664
best 0.947 0.951 0.746 0.767 0.638 0.664
Non-Methyl HT-SELEX, 1 experiments median 0.782 0.8 0.636 0.659 0.57 0.593
best 0.782 0.8 0.636 0.659 0.57 0.593
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyREVERBA (NR1D) {2.1.2.3} (TFClass)
TFClass IDTFClass: 2.1.2.3.1
HGNCHGNC:7962
MGIMGI:2444210
EntrezGene (human)GeneID:9572
(SSTAR profile)
EntrezGene (mouse)GeneID:217166
(SSTAR profile)
UniProt ID (human)NR1D1_HUMAN
UniProt ID (mouse)NR1D1_MOUSE
UniProt AC (human)P20393
(TFClass)
UniProt AC (mouse)Q3UV55
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 10 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013765.75235.75335.753667.75
021355.751666.753090.751891.75
03155.01183.0832.05835.0
044594.0132.03243.036.0
0518.02.07724.0261.0
0621.03.07967.014.0
0719.083.0387.07516.0
0818.05856.014.02117.0
097954.02.029.020.0
10494.01027.06227.0257.0
1122.090.0190.07703.0
124860.039.03089.017.0
134.03.07624.0374.0
1446.018.07921.020.0
15149.0301.0478.07077.0
1611.07491.084.0419.0
177087.526.5849.541.5
182144.251785.252053.252022.25
PFM
ACGT
010.470.0290.0420.458
020.1690.2080.3860.236
030.0190.1480.1040.729
040.5740.0160.4050.004
050.0020.00.9650.033
060.0030.00.9950.002
070.0020.010.0480.939
080.0020.7320.0020.264
090.9940.00.0040.002
100.0620.1280.7780.032
110.0030.0110.0240.962
120.6070.0050.3860.002
130.00.00.9520.047
140.0060.0020.990.002
150.0190.0380.060.884
160.0010.9360.010.052
170.8850.0030.1060.005
180.2680.2230.2560.253
PWM
ACGT
010.632-2.13-1.780.605
02-0.389-0.1830.434-0.056
03-2.545-0.525-0.8761.069
040.83-2.7030.482-3.959
05-4.595-6.1561.35-2.03
06-4.456-5.9451.381-4.815
07-4.546-3.157-1.6381.322
08-4.5951.073-4.8150.056
091.379-6.156-4.161-4.5
10-1.396-0.6661.134-2.045
11-4.414-3.078-2.3441.347
120.887-3.8830.434-4.645
13-5.771-5.9451.337-1.672
14-3.726-4.5951.375-4.5
15-2.584-1.888-1.4281.262
16-5.0191.319-3.145-1.559
171.264-4.244-0.855-3.824
180.069-0.1140.0260.01
Standard thresholds
P-value Threshold
0.001 -3.18349
0.0005 -1.38094
0.0001 2.42026