MotifNR1D1.H12INVIVO.0.P.B
Gene (human)NR1D1
(GeneCards)
Gene synonyms (human)EAR1, HREV, THRAL
Gene (mouse)Nr1d1
Gene synonyms (mouse)Ear1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length15
ConsensusMWbbRGGYCAvhddv
GC content52.29%
Information content (bits; total / per base)11.203 / 0.747
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 10 (64) 0.739 0.894 0.691 0.829 0.724 0.874 2.783 3.674 76.062 219.377

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.859 0.865 0.681 0.705 0.591 0.62
best 0.943 0.943 0.737 0.76 0.622 0.654
Methyl HT-SELEX, 1 experiments median 0.943 0.943 0.737 0.76 0.622 0.654
best 0.943 0.943 0.737 0.76 0.622 0.654
Non-Methyl HT-SELEX, 1 experiments median 0.775 0.787 0.625 0.65 0.559 0.585
best 0.775 0.787 0.625 0.65 0.559 0.585
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyThyroid hormone receptor-related {2.1.2} (TFClass)
TF subfamilyREVERBA (NR1D) {2.1.2.3} (TFClass)
TFClass IDTFClass: 2.1.2.3.1
HGNCHGNC:7962
MGIMGI:2444210
EntrezGene (human)GeneID:9572
(SSTAR profile)
EntrezGene (mouse)GeneID:217166
(SSTAR profile)
UniProt ID (human)NR1D1_HUMAN
UniProt ID (mouse)NR1D1_MOUSE
UniProt AC (human)P20393
(TFClass)
UniProt AC (mouse)Q3UV55
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 10 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01611.0250.049.090.0
02681.020.031.0268.0
0382.0363.0439.0116.0
0456.079.079.0786.0
05512.02.0463.023.0
0635.00.0874.091.0
0722.010.0952.016.0
0825.0178.0142.0655.0
0926.0892.020.062.0
10971.011.04.014.0
11170.0289.0433.0108.0
12195.0193.0190.0422.0
13284.0121.0458.0137.0
14198.0101.0501.0200.0
15169.0152.0548.0131.0
PFM
ACGT
010.6110.250.0490.09
020.6810.020.0310.268
030.0820.3630.4390.116
040.0560.0790.0790.786
050.5120.0020.4630.023
060.0350.00.8740.091
070.0220.010.9520.016
080.0250.1780.1420.655
090.0260.8920.020.062
100.9710.0110.0040.014
110.170.2890.4330.108
120.1950.1930.190.422
130.2840.1210.4580.137
140.1980.1010.5010.2
150.1690.1520.5480.131
PWM
ACGT
010.890.0-1.602-1.01
020.998-2.45-2.040.069
03-1.1010.3710.56-0.76
04-1.473-1.137-1.1371.141
050.713-4.2130.613-2.32
06-1.925-4.9821.247-0.999
07-2.362-3.0661.332-2.653
08-2.243-0.337-0.560.959
09-2.2061.267-2.45-1.374
101.352-2.985-3.783-2.773
11-0.3820.1440.546-0.83
12-0.247-0.257-0.2720.521
130.127-0.7180.602-0.596
14-0.231-0.8960.692-0.221
15-0.388-0.4930.781-0.64
Standard thresholds
P-value Threshold
0.001 4.44446
0.0005 5.35711
0.0001 7.22261