MotifNPAS2.H12INVIVO.0.M.D
Gene (human)NPAS2
(GeneCards)
Gene synonyms (human)BHLHE9, MOP4, PASD4
Gene (mouse)Npas2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length20
ConsensusvvRbRbRbndvACATGTGKn
GC content51.48%
Information content (bits; total / per base)14.55 / 0.727
Data sourcesMethyl-HT-SELEX
Aligned words379

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.982 0.977 0.911 0.903 0.818 0.816
best 0.998 0.997 0.994 0.991 0.984 0.978
Methyl HT-SELEX, 2 experiments median 0.857 0.852 0.797 0.791 0.747 0.741
best 0.988 0.983 0.969 0.957 0.921 0.903
Non-Methyl HT-SELEX, 2 experiments median 0.987 0.984 0.923 0.92 0.849 0.853
best 0.998 0.997 0.994 0.991 0.984 0.978

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.711 0.551 0.548 0.326
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-ARNT {1.2.5.2} (TFClass)
TFClass IDTFClass: 1.2.5.2.6
HGNCHGNC:7895
MGIMGI:109232
EntrezGene (human)GeneID:4862
(SSTAR profile)
EntrezGene (mouse)GeneID:18143
(SSTAR profile)
UniProt ID (human)NPAS2_HUMAN
UniProt ID (mouse)NPAS2_MOUSE
UniProt AC (human)Q99743
(TFClass)
UniProt AC (mouse)P97460
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01154.7562.75118.7542.75
0269.5209.575.524.5
03194.021.0134.030.0
0439.0101.076.0163.0
05124.014.0216.025.0
0637.080.093.0169.0
0735.017.0294.033.0
0845.049.0145.0140.0
09143.063.097.076.0
10190.017.0110.062.0
11208.049.097.025.0
12284.019.076.00.0
131.0376.02.00.0
14357.00.022.00.0
150.072.00.0307.0
1648.00.0331.00.0
171.0128.00.0250.0
182.00.0374.03.0
197.074.097.0201.0
2077.5103.588.5109.5
PFM
ACGT
010.4080.1660.3130.113
020.1830.5530.1990.065
030.5120.0550.3540.079
040.1030.2660.2010.43
050.3270.0370.570.066
060.0980.2110.2450.446
070.0920.0450.7760.087
080.1190.1290.3830.369
090.3770.1660.2560.201
100.5010.0450.290.164
110.5490.1290.2560.066
120.7490.050.2010.0
130.0030.9920.0050.0
140.9420.00.0580.0
150.00.190.00.81
160.1270.00.8730.0
170.0030.3380.00.66
180.0050.00.9870.008
190.0180.1950.2560.53
200.2040.2730.2340.289
PWM
ACGT
010.485-0.4040.223-0.777
02-0.3040.785-0.223-1.309
030.709-1.4540.342-1.117
04-0.8660.063-0.2170.536
050.265-1.8270.815-1.29
06-0.917-0.166-0.0180.572
07-0.97-1.651.122-1.026
08-0.728-0.6450.420.385
090.406-0.40.023-0.217
100.688-1.650.147-0.416
110.778-0.6450.023-1.29
121.087-1.547-0.217-4.172
13-3.6571.367-3.318-4.172
141.315-4.172-1.41-4.172
15-4.172-0.27-4.1721.165
16-0.665-4.1721.24-4.172
17-3.6570.297-4.1720.961
18-3.318-4.1721.361-3.066
19-2.429-0.2430.0230.744
20-0.1980.087-0.0670.143
Standard thresholds
P-value Threshold
0.001 3.26876
0.0005 4.44246
0.0001 6.85211