MotifNPAS2.H12INVITRO.2.S.B
Gene (human)NPAS2
(GeneCards)
Gene synonyms (human)BHLHE9, MOP4, PASD4
Gene (mouse)Npas2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length21
ConsensusvCACGTGbnnnMCACGTGYhn
GC content57.88%
Information content (bits; total / per base)21.092 / 1.004
Data sourcesHT-SELEX
Aligned words8715

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.981 0.972 0.898 0.887 0.784 0.783
best 1.0 1.0 0.999 0.998 0.994 0.992
Methyl HT-SELEX, 2 experiments median 0.831 0.814 0.766 0.75 0.706 0.694
best 0.969 0.952 0.922 0.897 0.848 0.823
Non-Methyl HT-SELEX, 2 experiments median 0.997 0.996 0.936 0.937 0.857 0.867
best 1.0 1.0 0.999 0.998 0.994 0.992

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.817 0.756 0.809 0.576
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyPAS {1.2.5} (TFClass)
TF subfamilyPAS-ARNT {1.2.5.2} (TFClass)
TFClass IDTFClass: 1.2.5.2.6
HGNCHGNC:7895
MGIMGI:109232
EntrezGene (human)GeneID:4862
(SSTAR profile)
EntrezGene (mouse)GeneID:18143
(SSTAR profile)
UniProt ID (human)NPAS2_HUMAN
UniProt ID (mouse)NPAS2_MOUSE
UniProt AC (human)Q99743
(TFClass)
UniProt AC (mouse)P97460
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
012698.02051.03062.0904.0
02731.57640.5145.5197.5
037191.0244.01040.0240.0
04151.07589.0268.0707.0
05615.0216.07657.0227.0
06153.0826.0357.07379.0
07148.0171.07818.0578.0
08625.02950.02075.03065.0
092728.02051.01475.02461.0
102827.01457.01802.02629.0
112639.01230.02760.02086.0
124685.02052.01859.0119.0
130.08715.00.00.0
148714.00.01.00.0
150.08712.00.03.0
160.00.08712.03.0
170.05.02.08708.0
180.01.08700.014.0
1984.02091.01858.04682.0
202534.53481.5821.51877.5
212489.752338.751700.752185.75
PFM
ACGT
010.310.2350.3510.104
020.0840.8770.0170.023
030.8250.0280.1190.028
040.0170.8710.0310.081
050.0710.0250.8790.026
060.0180.0950.0410.847
070.0170.020.8970.066
080.0720.3380.2380.352
090.3130.2350.1690.282
100.3240.1670.2070.302
110.3030.1410.3170.239
120.5380.2350.2130.014
130.01.00.00.0
141.00.00.00.0
150.01.00.00.0
160.00.01.00.0
170.00.0010.00.999
180.00.00.9980.002
190.010.240.2130.537
200.2910.3990.0940.215
210.2860.2680.1950.251
PWM
ACGT
010.214-0.060.34-0.878
02-1.0891.254-2.692-2.39
031.193-2.181-0.738-2.198
04-2.6551.247-2.088-1.123
05-1.262-2.3021.256-2.253
06-2.642-0.968-1.8031.219
07-2.675-2.5331.277-1.324
08-1.2460.303-0.0490.341
090.225-0.06-0.390.122
100.26-0.402-0.190.188
110.191-0.5710.236-0.043
120.765-0.06-0.159-2.89
13-6.8691.386-6.869-6.869
141.385-6.869-6.503-6.869
15-6.8691.385-6.869-6.026
16-6.869-6.8691.385-6.026
17-6.869-5.704-6.2361.385
18-6.869-6.5031.384-4.898
19-3.23-0.041-0.1590.764
200.1510.468-0.974-0.149
210.1330.071-0.2470.003
Standard thresholds
P-value Threshold
0.001 -3.86804
0.0005 -1.82799
0.0001 2.43501