| Motif | NPAS2.H12INVITRO.1.M.C |
| Gene (human) | NPAS2 (GeneCards) |
| Gene synonyms (human) | BHLHE9, MOP4, PASD4 |
| Gene (mouse) | Npas2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | C |
| Motif | NPAS2.H12INVITRO.1.M.C |
| Gene (human) | NPAS2 (GeneCards) |
| Gene synonyms (human) | BHLHE9, MOP4, PASD4 |
| Gene (mouse) | Npas2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | C |
| Motif length | 11 |
| Consensus | nvRCATGYGKn |
| GC content | 52.2% |
| Information content (bits; total / per base) | 10.97 / 0.997 |
| Data sources | Methyl-HT-SELEX |
| Aligned words | 9635 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.948 | 0.91 | 0.908 | 0.879 | 0.825 | 0.812 |
| best | 0.982 | 0.97 | 0.974 | 0.955 | 0.976 | 0.954 | |
| Methyl HT-SELEX, 2 experiments | median | 0.856 | 0.839 | 0.8 | 0.789 | 0.758 | 0.748 |
| best | 0.982 | 0.97 | 0.972 | 0.955 | 0.939 | 0.919 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.948 | 0.91 | 0.909 | 0.879 | 0.843 | 0.83 |
| best | 0.975 | 0.957 | 0.974 | 0.953 | 0.976 | 0.954 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.795 | 0.609 | 0.405 | 0.226 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic helix-loop-helix factors (bHLH) {1.2} (TFClass) |
| TF family | PAS {1.2.5} (TFClass) |
| TF subfamily | PAS-ARNT {1.2.5.2} (TFClass) |
| TFClass ID | TFClass: 1.2.5.2.6 |
| HGNC | HGNC:7895 |
| MGI | MGI:109232 |
| EntrezGene (human) | GeneID:4862 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18143 (SSTAR profile) |
| UniProt ID (human) | NPAS2_HUMAN |
| UniProt ID (mouse) | NPAS2_MOUSE |
| UniProt AC (human) | Q99743 (TFClass) |
| UniProt AC (mouse) | P97460 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 2 |
| PCM | NPAS2.H12INVITRO.1.M.C.pcm |
| PWM | NPAS2.H12INVITRO.1.M.C.pwm |
| PFM | NPAS2.H12INVITRO.1.M.C.pfm |
| Alignment | NPAS2.H12INVITRO.1.M.C.words.tsv |
| Threshold to P-value map | NPAS2.H12INVITRO.1.M.C.thr |
| Motif in other formats | |
| JASPAR format | NPAS2.H12INVITRO.1.M.C_jaspar_format.txt |
| MEME format | NPAS2.H12INVITRO.1.M.C_meme_format.meme |
| Transfac format | NPAS2.H12INVITRO.1.M.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2984.75 | 1564.75 | 2910.75 | 2174.75 |
| 02 | 3915.75 | 1667.75 | 2594.75 | 1456.75 |
| 03 | 5830.0 | 746.0 | 3047.0 | 12.0 |
| 04 | 26.0 | 9464.0 | 122.0 | 23.0 |
| 05 | 9258.0 | 3.0 | 369.0 | 5.0 |
| 06 | 1.0 | 997.0 | 29.0 | 8608.0 |
| 07 | 72.0 | 0.0 | 9560.0 | 3.0 |
| 08 | 44.0 | 3967.0 | 66.0 | 5558.0 |
| 09 | 33.0 | 90.0 | 9151.0 | 361.0 |
| 10 | 192.75 | 1978.75 | 2283.75 | 5179.75 |
| 11 | 2299.5 | 2753.5 | 1959.5 | 2622.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.31 | 0.162 | 0.302 | 0.226 |
| 02 | 0.406 | 0.173 | 0.269 | 0.151 |
| 03 | 0.605 | 0.077 | 0.316 | 0.001 |
| 04 | 0.003 | 0.982 | 0.013 | 0.002 |
| 05 | 0.961 | 0.0 | 0.038 | 0.001 |
| 06 | 0.0 | 0.103 | 0.003 | 0.893 |
| 07 | 0.007 | 0.0 | 0.992 | 0.0 |
| 08 | 0.005 | 0.412 | 0.007 | 0.577 |
| 09 | 0.003 | 0.009 | 0.95 | 0.037 |
| 10 | 0.02 | 0.205 | 0.237 | 0.538 |
| 11 | 0.239 | 0.286 | 0.203 | 0.272 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.214 | -0.431 | 0.189 | -0.102 |
| 02 | 0.486 | -0.367 | 0.074 | -0.502 |
| 03 | 0.883 | -1.17 | 0.235 | -5.128 |
| 04 | -4.445 | 1.368 | -2.965 | -4.557 |
| 05 | 1.346 | -6.121 | -1.871 | -5.801 |
| 06 | -6.596 | -0.881 | -4.344 | 1.273 |
| 07 | -3.48 | -6.958 | 1.378 | -6.121 |
| 08 | -3.953 | 0.499 | -3.564 | 0.836 |
| 09 | -4.224 | -3.263 | 1.334 | -1.893 |
| 10 | -2.515 | -0.196 | -0.053 | 0.765 |
| 11 | -0.046 | 0.134 | -0.206 | 0.085 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.165535 |
| 0.0005 | 5.397125 |
| 0.0001 | 7.867005 |