NOTO.H12RSNP.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NOTO.H12RSNP.0.SM.D
Gene (human)	NOTO (GeneCards)
Gene synonyms (human)
Gene (mouse)	Noto
Gene synonyms (mouse)	Not
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	13
Consensus	nvbYMATTAvbnn
GC content	40.24%
Information content (bits; total / per base)	9.813 / 0.755
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9834

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.95	0.918	0.914	0.873	0.865	0.823
Overall, 3 experiments	best	0.955	0.931	0.93	0.892	0.895	0.854
Methyl HT-SELEX, 1 experiments	median	0.941	0.906	0.914	0.873	0.865	0.823
Methyl HT-SELEX, 1 experiments	best	0.941	0.906	0.914	0.873	0.865	0.823
Non-Methyl HT-SELEX, 2 experiments	median	0.953	0.925	0.903	0.872	0.812	0.795
Non-Methyl HT-SELEX, 2 experiments	best	0.955	0.931	0.93	0.892	0.895	0.854

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	NOTO {3.1.2.20} (TFClass)
TFClass ID	TFClass: 3.1.2.20.1
HGNC	HGNC:31839
MGI	MGI:3053002
EntrezGene (human)	GeneID:344022 (SSTAR profile)
EntrezGene (mouse)	GeneID:384452 (SSTAR profile)
UniProt ID (human)	NOTO_HUMAN
UniProt ID (mouse)	NOTO_MOUSE
UniProt AC (human)	A8MTQ0 (TFClass)
UniProt AC (mouse)	Q5TIS6 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	NOTO.H12RSNP.0.SM.D.pcm
PWM	NOTO.H12RSNP.0.SM.D.pwm
PFM	NOTO.H12RSNP.0.SM.D.pfm
Alignment	NOTO.H12RSNP.0.SM.D.words.tsv
Threshold to P-value map	NOTO.H12RSNP.0.SM.D.thr
Motif in other formats
JASPAR format	NOTO.H12RSNP.0.SM.D_jaspar_format.txt
MEME format	NOTO.H12RSNP.0.SM.D_meme_format.meme
Transfac format	NOTO.H12RSNP.0.SM.D_transfac_format.txt
Homer format	NOTO.H12RSNP.0.SM.D_homer_format_0.001.txt NOTO.H12RSNP.0.SM.D_homer_format_0.0005.txt NOTO.H12RSNP.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2871.75	2685.75	2280.75	1995.75
02	1868.75	3969.75	2339.75	1655.75
03	1039.0	5719.0	1374.0	1702.0
04	1169.0	2117.0	528.0	6020.0
05	4133.0	5357.0	0.0	344.0
06	9583.0	0.0	251.0	0.0
07	0.0	5.0	0.0	9829.0
08	1.0	206.0	34.0	9593.0
09	9533.0	22.0	105.0	174.0
10	3402.0	1984.0	4030.0	418.0
11	662.0	4511.0	2519.0	2142.0
12	1509.25	2934.25	3283.25	2107.25
13	2208.0	3234.0	1951.0	2441.0

PFM

	A	C	G	T
01	0.292	0.273	0.232	0.203
02	0.19	0.404	0.238	0.168
03	0.106	0.582	0.14	0.173
04	0.119	0.215	0.054	0.612
05	0.42	0.545	0.0	0.035
06	0.974	0.0	0.026	0.0
07	0.0	0.001	0.0	0.999
08	0.0	0.021	0.003	0.975
09	0.969	0.002	0.011	0.018
10	0.346	0.202	0.41	0.043
11	0.067	0.459	0.256	0.218
12	0.153	0.298	0.334	0.214
13	0.225	0.329	0.198	0.248

PWM

	A	C	G	T
01	0.155	0.088	-0.075	-0.208
02	-0.274	0.479	-0.049	-0.395
03	-0.86	0.844	-0.581	-0.367
04	-0.742	-0.149	-1.535	0.895
05	0.519	0.778	-6.976	-1.961
06	1.36	-6.976	-2.274	-6.976
07	-6.976	-5.821	-6.976	1.385
08	-6.615	-2.469	-4.216	1.361
09	1.355	-4.618	-3.133	-2.636
10	0.325	-0.214	0.494	-1.767
11	-1.31	0.607	0.024	-0.138
12	-0.487	0.177	0.289	-0.154
13	-0.107	0.274	-0.231	-0.007

Standard thresholds

P-value	Threshold
0.001	5.01131
0.0005	6.01216
0.0001	7.52751