MotifNKX63.H12INVITRO.0.SM.B
Gene (human)NKX6-3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Nkx6-3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusnvWTTAATKASbbn
GC content30.49%
Information content (bits; total / per base)14.457 / 1.033
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words7231

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.99 0.983 0.982 0.972 0.964 0.949
best 0.992 0.986 0.986 0.977 0.972 0.96
Methyl HT-SELEX, 1 experiments median 0.987 0.979 0.979 0.967 0.955 0.938
best 0.987 0.979 0.979 0.967 0.955 0.938
Non-Methyl HT-SELEX, 1 experiments median 0.992 0.986 0.986 0.977 0.972 0.96
best 0.992 0.986 0.986 0.977 0.972 0.96
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK6 {3.1.2.19} (TFClass)
TFClass IDTFClass: 3.1.2.19.3
HGNCHGNC:26328
MGIMGI:1921811
EntrezGene (human)GeneID:157848
(SSTAR profile)
EntrezGene (mouse)GeneID:74561
(SSTAR profile)
UniProt ID (human)NKX63_HUMAN
UniProt ID (mouse)NKX63_MOUSE
UniProt AC (human)A6NJ46
(TFClass)
UniProt AC (mouse)Q3UHX8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011670.02106.01170.02285.0
022986.751978.751141.751123.75
034849.0585.0716.01081.0
04149.013.037.07032.0
050.02.00.07229.0
067231.00.00.00.0
077231.00.00.00.0
080.01.00.07230.0
090.026.03882.03323.0
106845.00.0386.00.0
1148.04366.02624.0193.0
12673.03173.02152.01233.0
13919.02545.01080.02687.0
141893.51801.51076.52459.5
PFM
ACGT
010.2310.2910.1620.316
020.4130.2740.1580.155
030.6710.0810.0990.149
040.0210.0020.0050.972
050.00.00.01.0
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.0040.5370.46
100.9470.00.0530.0
110.0070.6040.3630.027
120.0930.4390.2980.171
130.1270.3520.1490.372
140.2620.2490.1490.34
PWM
ACGT
01-0.0790.153-0.4340.234
020.5020.09-0.459-0.475
030.986-1.126-0.924-0.513
04-2.482-4.778-3.8321.357
05-6.703-6.061-6.7031.385
061.385-6.703-6.703-6.703
071.385-6.703-6.703-6.703
08-6.703-6.331-6.7031.385
09-6.703-4.1610.7640.608
101.331-6.703-1.539-6.703
11-3.5850.8810.372-2.227
12-0.9860.5620.174-0.382
13-0.6750.342-0.5140.396
140.046-0.003-0.5180.308
Standard thresholds
P-value Threshold
0.001 0.95701
0.0005 2.54656
0.0001 6.435615