| Motif | NKX62.H12INVIVO.0.SM.D |
| Gene (human) | NKX6-2 (GeneCards) |
| Gene synonyms (human) | GTX, NKX6B |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | NKX62.H12INVIVO.0.SM.D |
| Gene (human) | NKX6-2 (GeneCards) |
| Gene synonyms (human) | GTX, NKX6B |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 12 |
| Consensus | nvWTAATKAbbn |
| GC content | 32.11% |
| Information content (bits; total / per base) | 10.462 / 0.872 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9850 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.942 | 0.906 | 0.917 | 0.876 | 0.866 | 0.826 |
| best | 0.96 | 0.936 | 0.942 | 0.91 | 0.904 | 0.866 | |
| Methyl HT-SELEX, 2 experiments | median | 0.918 | 0.87 | 0.896 | 0.844 | 0.858 | 0.807 |
| best | 0.947 | 0.914 | 0.923 | 0.884 | 0.882 | 0.84 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.945 | 0.91 | 0.923 | 0.882 | 0.875 | 0.837 |
| best | 0.96 | 0.936 | 0.942 | 0.91 | 0.904 | 0.866 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | NK6 {3.1.2.19} (TFClass) |
| TFClass ID | TFClass: 3.1.2.19.2 |
| HGNC | HGNC:19321 |
| MGI | |
| EntrezGene (human) | GeneID:84504 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | NKX62_HUMAN |
| UniProt ID (mouse) | |
| UniProt AC (human) | Q9C056 (TFClass) |
| UniProt AC (mouse) | |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | NKX62.H12INVIVO.0.SM.D.pcm |
| PWM | NKX62.H12INVIVO.0.SM.D.pwm |
| PFM | NKX62.H12INVIVO.0.SM.D.pfm |
| Alignment | NKX62.H12INVIVO.0.SM.D.words.tsv |
| Threshold to P-value map | NKX62.H12INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | NKX62.H12INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | NKX62.H12INVIVO.0.SM.D_meme_format.meme |
| Transfac format | NKX62.H12INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2477.75 | 2673.75 | 2322.75 | 2375.75 |
| 02 | 4146.5 | 1795.5 | 2622.5 | 1285.5 |
| 03 | 1301.0 | 434.0 | 1189.0 | 6926.0 |
| 04 | 3.0 | 383.0 | 0.0 | 9464.0 |
| 05 | 9722.0 | 0.0 | 127.0 | 1.0 |
| 06 | 9850.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 5.0 | 1.0 | 9844.0 |
| 08 | 316.0 | 726.0 | 3804.0 | 5004.0 |
| 09 | 7180.0 | 20.0 | 2632.0 | 18.0 |
| 10 | 947.0 | 4210.0 | 3268.0 | 1425.0 |
| 11 | 1277.5 | 3323.5 | 3294.5 | 1954.5 |
| 12 | 2189.0 | 2806.0 | 2313.0 | 2542.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.252 | 0.271 | 0.236 | 0.241 |
| 02 | 0.421 | 0.182 | 0.266 | 0.131 |
| 03 | 0.132 | 0.044 | 0.121 | 0.703 |
| 04 | 0.0 | 0.039 | 0.0 | 0.961 |
| 05 | 0.987 | 0.0 | 0.013 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.001 | 0.0 | 0.999 |
| 08 | 0.032 | 0.074 | 0.386 | 0.508 |
| 09 | 0.729 | 0.002 | 0.267 | 0.002 |
| 10 | 0.096 | 0.427 | 0.332 | 0.145 |
| 11 | 0.13 | 0.337 | 0.334 | 0.198 |
| 12 | 0.222 | 0.285 | 0.235 | 0.258 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.006 | 0.082 | -0.058 | -0.036 |
| 02 | 0.521 | -0.316 | 0.063 | -0.649 |
| 03 | -0.637 | -1.732 | -0.727 | 1.034 |
| 04 | -6.142 | -1.856 | -6.977 | 1.346 |
| 05 | 1.373 | -6.977 | -2.948 | -6.616 |
| 06 | 1.386 | -6.977 | -6.977 | -6.977 |
| 07 | -6.977 | -5.822 | -6.616 | 1.385 |
| 08 | -2.047 | -1.219 | 0.435 | 0.709 |
| 09 | 1.07 | -4.705 | 0.067 | -4.799 |
| 10 | -0.954 | 0.536 | 0.283 | -0.546 |
| 11 | -0.655 | 0.3 | 0.291 | -0.231 |
| 12 | -0.118 | 0.13 | -0.063 | 0.032 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.799325 |
| 0.0005 | 5.910265 |
| 0.0001 | 7.66143 |