MotifNKX62.H12INVITRO.0.SM.B
Gene (human)NKX6-2
(GeneCards)
Gene synonyms (human)GTX, NKX6B
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length12
ConsensusnvWTAATKAbbn
GC content32.11%
Information content (bits; total / per base)10.462 / 0.872
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9850

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.942 0.906 0.917 0.876 0.866 0.826
best 0.96 0.936 0.942 0.91 0.904 0.866
Methyl HT-SELEX, 2 experiments median 0.918 0.87 0.896 0.844 0.858 0.807
best 0.947 0.914 0.923 0.884 0.882 0.84
Non-Methyl HT-SELEX, 6 experiments median 0.945 0.91 0.923 0.882 0.875 0.837
best 0.96 0.936 0.942 0.91 0.904 0.866
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK6 {3.1.2.19} (TFClass)
TFClass IDTFClass: 3.1.2.19.2
HGNCHGNC:19321
MGI
EntrezGene (human)GeneID:84504
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NKX62_HUMAN
UniProt ID (mouse)
UniProt AC (human)Q9C056
(TFClass)
UniProt AC (mouse)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012477.752673.752322.752375.75
024146.51795.52622.51285.5
031301.0434.01189.06926.0
043.0383.00.09464.0
059722.00.0127.01.0
069850.00.00.00.0
070.05.01.09844.0
08316.0726.03804.05004.0
097180.020.02632.018.0
10947.04210.03268.01425.0
111277.53323.53294.51954.5
122189.02806.02313.02542.0
PFM
ACGT
010.2520.2710.2360.241
020.4210.1820.2660.131
030.1320.0440.1210.703
040.00.0390.00.961
050.9870.00.0130.0
061.00.00.00.0
070.00.0010.00.999
080.0320.0740.3860.508
090.7290.0020.2670.002
100.0960.4270.3320.145
110.130.3370.3340.198
120.2220.2850.2350.258
PWM
ACGT
010.0060.082-0.058-0.036
020.521-0.3160.063-0.649
03-0.637-1.732-0.7271.034
04-6.142-1.856-6.9771.346
051.373-6.977-2.948-6.616
061.386-6.977-6.977-6.977
07-6.977-5.822-6.6161.385
08-2.047-1.2190.4350.709
091.07-4.7050.067-4.799
10-0.9540.5360.283-0.546
11-0.6550.30.291-0.231
12-0.1180.13-0.0630.032
Standard thresholds
P-value Threshold
0.001 4.799325
0.0005 5.910265
0.0001 7.66143