MotifNKX61.H12INVIVO.0.PS.A
Gene (human)NKX6-1
(GeneCards)
Gene synonyms (human)NKX6A
Gene (mouse)Nkx6-1
Gene synonyms (mouse)Nkx6.1, Nkx6a
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length20
ConsensusdRhdRATKdvndWWWRAWdd
GC content30.16%
Information content (bits; total / per base)12.426 / 0.621
Data sourcesChIP-Seq + HT-SELEX
Aligned words997

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (19) 0.81 0.87 0.696 0.777 0.84 0.893 3.284 3.743 188.013 324.796

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 6 experiments median 0.735 0.701 0.634 0.623 0.566 0.574
best 0.959 0.941 0.908 0.88 0.821 0.798
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK6 {3.1.2.19} (TFClass)
TFClass IDTFClass: 3.1.2.19.1
HGNCHGNC:7839
MGIMGI:1206039
EntrezGene (human)GeneID:4825
(SSTAR profile)
EntrezGene (mouse)GeneID:18096
(SSTAR profile)
UniProt ID (human)NKX61_HUMAN
UniProt ID (mouse)NKX61_MOUSE
UniProt AC (human)P78426
(TFClass)
UniProt AC (mouse)Q99MA9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 6
Methyl-HT-SELEX 0
PCM
ACGT
01243.080.0528.0146.0
02691.086.0135.085.0
03160.0247.0126.0464.0
04297.051.0141.0508.0
05608.048.0268.073.0
06973.08.09.07.0
0751.037.098.0811.0
0833.081.0567.0316.0
09382.067.0405.0143.0
10126.0351.0420.0100.0
11349.0215.0135.0298.0
12398.095.0121.0383.0
13382.045.048.0522.0
14285.048.040.0624.0
15119.083.038.0757.0
16630.095.0248.024.0
17981.00.012.04.0
18110.038.062.0787.0
19163.053.0376.0405.0
20380.083.0425.0109.0
PFM
ACGT
010.2440.080.530.146
020.6930.0860.1350.085
030.160.2480.1260.465
040.2980.0510.1410.51
050.610.0480.2690.073
060.9760.0080.0090.007
070.0510.0370.0980.813
080.0330.0810.5690.317
090.3830.0670.4060.143
100.1260.3520.4210.1
110.350.2160.1350.299
120.3990.0950.1210.384
130.3830.0450.0480.524
140.2860.0480.040.626
150.1190.0830.0380.759
160.6320.0950.2490.024
170.9840.00.0120.004
180.110.0380.0620.789
190.1630.0530.3770.406
200.3810.0830.4260.109
PWM
ACGT
01-0.025-1.1220.747-0.53
021.015-1.051-0.607-1.063
03-0.439-0.009-0.6750.618
040.174-1.56-0.5640.709
050.888-1.6190.072-1.212
061.357-3.251-3.153-3.359
07-1.56-1.869-0.9231.175
08-1.978-1.110.8180.236
090.425-1.2950.483-0.551
10-0.6750.340.519-0.903
110.335-0.147-0.6070.178
120.465-0.953-0.7150.427
130.425-1.681-1.6190.736
140.133-1.619-1.7940.914
15-0.732-1.086-1.8431.106
160.923-0.953-0.005-2.278
171.365-4.979-2.906-3.78
18-0.809-1.843-1.3711.145
19-0.421-1.5230.4090.483
200.419-1.0860.531-0.818
Standard thresholds
P-value Threshold
0.001 4.14786
0.0005 5.09286
0.0001 7.05116