Motif | NKX61.H12CORE.2.S.B |
Gene (human) | NKX6-1 (GeneCards) |
Gene synonyms (human) | NKX6A |
Gene (mouse) | Nkx6-1 |
Gene synonyms (mouse) | Nkx6.1, Nkx6a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif | NKX61.H12CORE.2.S.B |
Gene (human) | NKX6-1 (GeneCards) |
Gene synonyms (human) | NKX6A |
Gene (mouse) | Nkx6-1 |
Gene synonyms (mouse) | Nkx6.1, Nkx6a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 2 |
Quality | B |
Motif length | 13 |
Consensus | nndTTAATKAbnn |
GC content | 29.54% |
Information content (bits; total / per base) | 11.784 / 0.906 |
Data sources | HT-SELEX |
Aligned words | 9523 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 3 (19) | 0.736 | 0.775 | 0.546 | 0.609 | 0.696 | 0.778 | 1.854 | 2.248 | 62.959 | 129.292 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Non-Methyl HT-SELEX, 6 experiments | median | 0.909 | 0.87 | 0.808 | 0.78 | 0.676 | 0.682 |
best | 0.98 | 0.967 | 0.97 | 0.952 | 0.948 | 0.925 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | NK6 {3.1.2.19} (TFClass) |
TFClass ID | TFClass: 3.1.2.19.1 |
HGNC | HGNC:7839 |
MGI | MGI:1206039 |
EntrezGene (human) | GeneID:4825 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18096 (SSTAR profile) |
UniProt ID (human) | NKX61_HUMAN |
UniProt ID (mouse) | NKX61_MOUSE |
UniProt AC (human) | P78426 (TFClass) |
UniProt AC (mouse) | Q99MA9 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 3 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 0 |
PCM | NKX61.H12CORE.2.S.B.pcm |
PWM | NKX61.H12CORE.2.S.B.pwm |
PFM | NKX61.H12CORE.2.S.B.pfm |
Alignment | NKX61.H12CORE.2.S.B.words.tsv |
Threshold to P-value map | NKX61.H12CORE.2.S.B.thr |
Motif in other formats | |
JASPAR format | NKX61.H12CORE.2.S.B_jaspar_format.txt |
MEME format | NKX61.H12CORE.2.S.B_meme_format.meme |
Transfac format | NKX61.H12CORE.2.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 2222.75 | 2666.75 | 2094.75 | 2538.75 |
02 | 2616.25 | 2746.25 | 1993.25 | 2167.25 |
03 | 4792.0 | 1326.0 | 1764.0 | 1641.0 |
04 | 1032.0 | 112.0 | 504.0 | 7875.0 |
05 | 0.0 | 32.0 | 0.0 | 9491.0 |
06 | 9521.0 | 0.0 | 2.0 | 0.0 |
07 | 9523.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 2.0 | 9521.0 |
09 | 105.0 | 86.0 | 3692.0 | 5640.0 |
10 | 7563.0 | 10.0 | 1940.0 | 10.0 |
11 | 877.0 | 4189.0 | 3056.0 | 1401.0 |
12 | 1318.5 | 3346.5 | 2732.5 | 2125.5 |
13 | 2383.0 | 2456.0 | 1823.0 | 2861.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.233 | 0.28 | 0.22 | 0.267 |
02 | 0.275 | 0.288 | 0.209 | 0.228 |
03 | 0.503 | 0.139 | 0.185 | 0.172 |
04 | 0.108 | 0.012 | 0.053 | 0.827 |
05 | 0.0 | 0.003 | 0.0 | 0.997 |
06 | 1.0 | 0.0 | 0.0 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.0 | 1.0 |
09 | 0.011 | 0.009 | 0.388 | 0.592 |
10 | 0.794 | 0.001 | 0.204 | 0.001 |
11 | 0.092 | 0.44 | 0.321 | 0.147 |
12 | 0.138 | 0.351 | 0.287 | 0.223 |
13 | 0.25 | 0.258 | 0.191 | 0.3 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.069 | 0.113 | -0.128 | 0.064 |
02 | 0.094 | 0.143 | -0.177 | -0.094 |
03 | 0.699 | -0.584 | -0.299 | -0.372 |
04 | -0.835 | -3.037 | -1.549 | 1.196 |
05 | -6.947 | -4.241 | -6.947 | 1.382 |
06 | 1.385 | -6.947 | -6.32 | -6.947 |
07 | 1.386 | -6.947 | -6.947 | -6.947 |
08 | -6.947 | -6.947 | -6.32 | 1.385 |
09 | -3.101 | -3.296 | 0.438 | 0.862 |
10 | 1.155 | -5.267 | -0.205 | -5.267 |
11 | -0.997 | 0.565 | 0.249 | -0.53 |
12 | -0.59 | 0.34 | 0.138 | -0.113 |
13 | 0.001 | 0.031 | -0.267 | 0.184 |
P-value | Threshold |
---|---|
0.001 | 3.35867 |
0.0005 | 5.159365 |
0.0001 | 7.78131 |