MotifNKX61.H12CORE.2.S.B
Gene (human)NKX6-1
(GeneCards)
Gene synonyms (human)NKX6A
Gene (mouse)Nkx6-1
Gene synonyms (mouse)Nkx6.1, Nkx6a
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length13
ConsensusnndTTAATKAbnn
GC content29.54%
Information content (bits; total / per base)11.784 / 0.906
Data sourcesHT-SELEX
Aligned words9523

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 3 (19) 0.736 0.775 0.546 0.609 0.696 0.778 1.854 2.248 62.959 129.292

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 6 experiments median 0.909 0.87 0.808 0.78 0.676 0.682
best 0.98 0.967 0.97 0.952 0.948 0.925
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK6 {3.1.2.19} (TFClass)
TFClass IDTFClass: 3.1.2.19.1
HGNCHGNC:7839
MGIMGI:1206039
EntrezGene (human)GeneID:4825
(SSTAR profile)
EntrezGene (mouse)GeneID:18096
(SSTAR profile)
UniProt ID (human)NKX61_HUMAN
UniProt ID (mouse)NKX61_MOUSE
UniProt AC (human)P78426
(TFClass)
UniProt AC (mouse)Q99MA9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 3 mouse
HT-SELEX 6
Methyl-HT-SELEX 0
PCM
ACGT
012222.752666.752094.752538.75
022616.252746.251993.252167.25
034792.01326.01764.01641.0
041032.0112.0504.07875.0
050.032.00.09491.0
069521.00.02.00.0
079523.00.00.00.0
080.00.02.09521.0
09105.086.03692.05640.0
107563.010.01940.010.0
11877.04189.03056.01401.0
121318.53346.52732.52125.5
132383.02456.01823.02861.0
PFM
ACGT
010.2330.280.220.267
020.2750.2880.2090.228
030.5030.1390.1850.172
040.1080.0120.0530.827
050.00.0030.00.997
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.0110.0090.3880.592
100.7940.0010.2040.001
110.0920.440.3210.147
120.1380.3510.2870.223
130.250.2580.1910.3
PWM
ACGT
01-0.0690.113-0.1280.064
020.0940.143-0.177-0.094
030.699-0.584-0.299-0.372
04-0.835-3.037-1.5491.196
05-6.947-4.241-6.9471.382
061.385-6.947-6.32-6.947
071.386-6.947-6.947-6.947
08-6.947-6.947-6.321.385
09-3.101-3.2960.4380.862
101.155-5.267-0.205-5.267
11-0.9970.5650.249-0.53
12-0.590.340.138-0.113
130.0010.031-0.2670.184
Standard thresholds
P-value Threshold
0.001 3.35867
0.0005 5.159365
0.0001 7.78131