Motif | NKX61.H12CORE.1.P.B |
Gene (human) | NKX6-1 (GeneCards) |
Gene synonyms (human) | NKX6A |
Gene (mouse) | Nkx6-1 |
Gene synonyms (mouse) | Nkx6.1, Nkx6a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | NKX61.H12CORE.1.P.B |
Gene (human) | NKX6-1 (GeneCards) |
Gene synonyms (human) | NKX6A |
Gene (mouse) | Nkx6-1 |
Gene synonyms (mouse) | Nkx6.1, Nkx6a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 8 |
Consensus | hTAATGRb |
GC content | 30.23% |
Information content (bits; total / per base) | 9.229 / 1.154 |
Data sources | ChIP-Seq |
Aligned words | 997 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Mouse | 3 (19) | 0.755 | 0.813 | 0.585 | 0.687 | 0.685 | 0.789 | 1.694 | 2.223 | 62.854 | 123.721 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Non-Methyl HT-SELEX, 6 experiments | median | 0.861 | 0.815 | 0.775 | 0.739 | 0.667 | 0.66 |
best | 0.983 | 0.974 | 0.96 | 0.944 | 0.931 | 0.906 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | NK6 {3.1.2.19} (TFClass) |
TFClass ID | TFClass: 3.1.2.19.1 |
HGNC | HGNC:7839 |
MGI | MGI:1206039 |
EntrezGene (human) | GeneID:4825 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18096 (SSTAR profile) |
UniProt ID (human) | NKX61_HUMAN |
UniProt ID (mouse) | NKX61_MOUSE |
UniProt AC (human) | P78426 (TFClass) |
UniProt AC (mouse) | Q99MA9 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 3 mouse |
HT-SELEX | 6 |
Methyl-HT-SELEX | 0 |
PCM | NKX61.H12CORE.1.P.B.pcm |
PWM | NKX61.H12CORE.1.P.B.pwm |
PFM | NKX61.H12CORE.1.P.B.pfm |
Alignment | NKX61.H12CORE.1.P.B.words.tsv |
Threshold to P-value map | NKX61.H12CORE.1.P.B.thr |
Motif in other formats | |
JASPAR format | NKX61.H12CORE.1.P.B_jaspar_format.txt |
MEME format | NKX61.H12CORE.1.P.B_meme_format.meme |
Transfac format | NKX61.H12CORE.1.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 131.0 | 224.0 | 68.0 | 574.0 |
02 | 80.0 | 17.0 | 11.0 | 889.0 |
03 | 843.0 | 15.0 | 126.0 | 13.0 |
04 | 989.0 | 1.0 | 3.0 | 4.0 |
05 | 4.0 | 3.0 | 3.0 | 987.0 |
06 | 1.0 | 9.0 | 899.0 | 88.0 |
07 | 623.0 | 16.0 | 298.0 | 60.0 |
08 | 124.0 | 300.0 | 418.0 | 155.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.131 | 0.225 | 0.068 | 0.576 |
02 | 0.08 | 0.017 | 0.011 | 0.892 |
03 | 0.846 | 0.015 | 0.126 | 0.013 |
04 | 0.992 | 0.001 | 0.003 | 0.004 |
05 | 0.004 | 0.003 | 0.003 | 0.99 |
06 | 0.001 | 0.009 | 0.902 | 0.088 |
07 | 0.625 | 0.016 | 0.299 | 0.06 |
08 | 0.124 | 0.301 | 0.419 | 0.155 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.637 | -0.106 | -1.281 | 0.83 |
02 | -1.122 | -2.595 | -2.982 | 1.267 |
03 | 1.214 | -2.708 | -0.675 | -2.836 |
04 | 1.373 | -4.522 | -3.972 | -3.78 |
05 | -3.78 | -3.972 | -3.972 | 1.371 |
06 | -4.522 | -3.153 | 1.278 | -1.029 |
07 | 0.912 | -2.65 | 0.178 | -1.403 |
08 | -0.691 | 0.184 | 0.514 | -0.471 |
P-value | Threshold |
---|---|
0.001 | 4.98607 |
0.0005 | 5.930035 |
0.0001 | 7.533245 |