MotifNKX32.H12INVITRO.0.PSM.A
Gene (human)NKX3-2
(GeneCards)
Gene synonyms (human)BAPX1, NKX3B
Gene (mouse)Nkx3-2
Gene synonyms (mouse)Bapx1, Nkx-3.2, Nkx3b
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length10
ConsensusnhTAAGTGbn
GC content41.01%
Information content (bits; total / per base)10.198 / 1.02
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9976

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (13) 0.863 0.975 0.802 0.949 0.794 0.929 2.48 3.372 229.292 419.237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.976 0.963 0.921 0.904 0.802 0.808
best 0.994 0.991 0.978 0.971 0.894 0.873
Methyl HT-SELEX, 1 experiments median 0.93 0.897 0.848 0.816 0.726 0.719
best 0.93 0.897 0.848 0.816 0.726 0.719
Non-Methyl HT-SELEX, 3 experiments median 0.981 0.97 0.957 0.94 0.864 0.868
best 0.994 0.991 0.978 0.971 0.894 0.873
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK3 {3.1.2.16} (TFClass)
TFClass IDTFClass: 3.1.2.16.2
HGNCHGNC:951
MGIMGI:108015
EntrezGene (human)GeneID:579
(SSTAR profile)
EntrezGene (mouse)GeneID:12020
(SSTAR profile)
UniProt ID (human)NKX32_HUMAN
UniProt ID (mouse)NKX32_MOUSE
UniProt AC (human)P78367
(TFClass)
UniProt AC (mouse)P97503
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012316.52585.53321.51752.5
021649.251915.251445.254966.25
03407.0407.0643.08519.0
049783.00.0181.012.0
059976.00.00.00.0
064.08.09918.046.0
07195.056.0276.09449.0
081906.089.07873.0108.0
09932.753272.753964.751805.75
101809.02526.02425.03216.0
PFM
ACGT
010.2320.2590.3330.176
020.1650.1920.1450.498
030.0410.0410.0640.854
040.9810.00.0180.001
051.00.00.00.0
060.00.0010.9940.005
070.020.0060.0280.947
080.1910.0090.7890.011
090.0930.3280.3970.181
100.1810.2530.2430.322
PWM
ACGT
01-0.0740.0360.286-0.352
02-0.413-0.264-0.5450.688
03-1.808-1.808-1.3531.228
041.366-6.989-2.611-5.162
051.386-6.989-6.989-6.989
06-5.982-5.491.38-3.945
07-2.538-3.757-2.1941.331
08-0.269-3.3081.149-3.119
09-0.9820.2720.463-0.323
10-0.3210.013-0.0280.254
Standard thresholds
P-value Threshold
0.001 4.637045
0.0005 5.685825
0.0001 7.75514