MotifNKX32.H12CORE.1.S.B
Gene (human)NKX3-2
(GeneCards)
Gene synonyms (human)BAPX1, NKX3B
Gene (mouse)Nkx3-2
Gene synonyms (mouse)Bapx1, Nkx-3.2, Nkx3b
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length20
ConsensusnYTAAGTGShhhYWWRdddn
GC content41.03%
Information content (bits; total / per base)16.767 / 0.838
Data sourcesHT-SELEX
Aligned words1560

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (13) 0.835 0.954 0.764 0.908 0.761 0.915 2.526 3.858 197.638 375.292

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.949 0.931 0.862 0.843 0.735 0.741
best 0.993 0.991 0.938 0.932 0.851 0.823
Methyl HT-SELEX, 1 experiments median 0.894 0.857 0.798 0.766 0.69 0.681
best 0.894 0.857 0.798 0.766 0.69 0.681
Non-Methyl HT-SELEX, 3 experiments median 0.961 0.942 0.922 0.893 0.78 0.797
best 0.993 0.991 0.938 0.932 0.851 0.823
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK3 {3.1.2.16} (TFClass)
TFClass IDTFClass: 3.1.2.16.2
HGNCHGNC:951
MGIMGI:108015
EntrezGene (human)GeneID:579
(SSTAR profile)
EntrezGene (mouse)GeneID:12020
(SSTAR profile)
UniProt ID (human)NKX32_HUMAN
UniProt ID (mouse)NKX32_MOUSE
UniProt AC (human)P78367
(TFClass)
UniProt AC (mouse)P97503
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01280.25605.25339.25335.25
02186.0249.0101.01024.0
0324.044.031.01461.0
041553.00.07.00.0
051559.00.00.01.0
060.00.01559.01.0
073.00.03.01554.0
0857.00.01503.00.0
0913.0456.01034.057.0
10174.0876.0156.0354.0
11651.0502.073.0334.0
12555.0695.076.0234.0
13273.0385.023.0879.0
14226.032.0108.01194.0
15929.039.081.0511.0
16955.056.0319.0230.0
17314.0201.0681.0364.0
18249.0176.0561.0574.0
19322.75247.75697.75291.75
20387.5351.5532.5288.5
PFM
ACGT
010.180.3880.2170.215
020.1190.160.0650.656
030.0150.0280.020.937
040.9960.00.0040.0
050.9990.00.00.001
060.00.00.9990.001
070.0020.00.0020.996
080.0370.00.9630.0
090.0080.2920.6630.037
100.1120.5620.10.227
110.4170.3220.0470.214
120.3560.4460.0490.15
130.1750.2470.0150.563
140.1450.0210.0690.765
150.5960.0250.0520.328
160.6120.0360.2040.147
170.2010.1290.4370.233
180.160.1130.360.368
190.2070.1590.4470.187
200.2480.2250.3410.185
PWM
ACGT
01-0.3290.438-0.139-0.151
02-0.735-0.446-1.3380.962
03-2.719-2.146-2.4791.317
041.378-5.362-3.792-5.362
051.382-5.362-5.362-4.928
06-5.362-5.3621.382-4.928
07-4.394-5.362-4.3941.379
08-1.896-5.3621.346-5.362
09-3.2740.1560.972-1.896
10-0.8010.807-0.909-0.096
110.510.251-1.656-0.154
120.3510.576-1.616-0.508
13-0.355-0.013-2.7580.81
14-0.542-2.449-1.2721.116
150.865-2.261-1.5540.269
160.893-1.913-0.2-0.525
17-0.216-0.6580.555-0.069
18-0.446-0.790.3620.385
19-0.188-0.4510.58-0.289
20-0.006-0.1030.31-0.3
Standard thresholds
P-value Threshold
0.001 1.23306
0.0005 2.72656
0.0001 5.81651