Motif | NKX31.H12CORE.0.PSM.A |
Gene (human) | NKX3-1 (GeneCards) |
Gene synonyms (human) | NKX3.1, NKX3A |
Gene (mouse) | Nkx3-1 |
Gene synonyms (mouse) | Nkx-3.1, Nkx3a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif | NKX31.H12CORE.0.PSM.A |
Gene (human) | NKX3-1 (GeneCards) |
Gene synonyms (human) | NKX3.1, NKX3A |
Gene (mouse) | Nkx3-1 |
Gene synonyms (mouse) | Nkx-3.1, Nkx3a |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | A |
Motif length | 14 |
Consensus | nYTAAGTGSbhhhh |
GC content | 41.87% |
Information content (bits; total / per base) | 13.218 / 0.944 |
Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
Aligned words | 9937 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 3 (20) | 0.695 | 0.772 | 0.513 | 0.62 | 0.614 | 0.687 | 1.404 | 1.718 | 39.689 | 101.886 |
Mouse | 1 (5) | 0.671 | 0.688 | 0.481 | 0.497 | 0.556 | 0.572 | 1.194 | 1.248 | 43.523 | 63.585 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 6 experiments | median | 0.97 | 0.957 | 0.909 | 0.895 | 0.812 | 0.815 |
best | 0.998 | 0.996 | 0.989 | 0.986 | 0.977 | 0.967 | |
Methyl HT-SELEX, 1 experiments | median | 0.992 | 0.987 | 0.988 | 0.981 | 0.977 | 0.967 |
best | 0.992 | 0.987 | 0.988 | 0.981 | 0.977 | 0.967 | |
Non-Methyl HT-SELEX, 5 experiments | median | 0.953 | 0.938 | 0.841 | 0.826 | 0.71 | 0.717 |
best | 0.998 | 0.996 | 0.989 | 0.986 | 0.954 | 0.935 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | NK3 {3.1.2.16} (TFClass) |
TFClass ID | TFClass: 3.1.2.16.1 |
HGNC | HGNC:7838 |
MGI | MGI:97352 |
EntrezGene (human) | GeneID:4824 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18095 (SSTAR profile) |
UniProt ID (human) | NKX31_HUMAN |
UniProt ID (mouse) | NKX31_MOUSE |
UniProt AC (human) | Q99801 (TFClass) |
UniProt AC (mouse) | P97436 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 3 human, 1 mouse |
HT-SELEX | 5 |
Methyl-HT-SELEX | 1 |
PCM | NKX31.H12CORE.0.PSM.A.pcm |
PWM | NKX31.H12CORE.0.PSM.A.pwm |
PFM | NKX31.H12CORE.0.PSM.A.pfm |
Alignment | NKX31.H12CORE.0.PSM.A.words.tsv |
Threshold to P-value map | NKX31.H12CORE.0.PSM.A.thr |
Motif in other formats | |
JASPAR format | NKX31.H12CORE.0.PSM.A_jaspar_format.txt |
MEME format | NKX31.H12CORE.0.PSM.A_meme_format.meme |
Transfac format | NKX31.H12CORE.0.PSM.A_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1944.0 | 3192.0 | 2469.0 | 2332.0 |
02 | 1310.25 | 1373.25 | 949.25 | 6304.25 |
03 | 161.0 | 139.0 | 266.0 | 9371.0 |
04 | 9769.0 | 0.0 | 159.0 | 9.0 |
05 | 9933.0 | 3.0 | 0.0 | 1.0 |
06 | 8.0 | 0.0 | 9912.0 | 17.0 |
07 | 21.0 | 18.0 | 15.0 | 9883.0 |
08 | 899.0 | 6.0 | 9017.0 | 15.0 |
09 | 173.0 | 2681.0 | 6556.0 | 527.0 |
10 | 1094.0 | 3655.0 | 1472.0 | 3716.0 |
11 | 3554.0 | 2453.0 | 896.0 | 3034.0 |
12 | 2511.0 | 5075.0 | 872.0 | 1479.0 |
13 | 1623.0 | 3082.0 | 979.0 | 4253.0 |
14 | 1894.25 | 1821.25 | 1190.25 | 5031.25 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.196 | 0.321 | 0.248 | 0.235 |
02 | 0.132 | 0.138 | 0.096 | 0.634 |
03 | 0.016 | 0.014 | 0.027 | 0.943 |
04 | 0.983 | 0.0 | 0.016 | 0.001 |
05 | 1.0 | 0.0 | 0.0 | 0.0 |
06 | 0.001 | 0.0 | 0.997 | 0.002 |
07 | 0.002 | 0.002 | 0.002 | 0.995 |
08 | 0.09 | 0.001 | 0.907 | 0.002 |
09 | 0.017 | 0.27 | 0.66 | 0.053 |
10 | 0.11 | 0.368 | 0.148 | 0.374 |
11 | 0.358 | 0.247 | 0.09 | 0.305 |
12 | 0.253 | 0.511 | 0.088 | 0.149 |
13 | 0.163 | 0.31 | 0.099 | 0.428 |
14 | 0.191 | 0.183 | 0.12 | 0.506 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.245 | 0.25 | -0.006 | -0.063 |
02 | -0.639 | -0.592 | -0.961 | 0.931 |
03 | -2.723 | -2.868 | -2.227 | 1.327 |
04 | 1.369 | -6.985 | -2.735 | -5.394 |
05 | 1.385 | -6.151 | -6.985 | -6.624 |
06 | -5.486 | -6.985 | 1.383 | -4.858 |
07 | -4.67 | -4.808 | -4.968 | 1.38 |
08 | -1.015 | -5.702 | 1.288 | -4.968 |
09 | -2.652 | 0.076 | 0.97 | -1.547 |
10 | -0.819 | 0.386 | -0.523 | 0.402 |
11 | 0.358 | -0.013 | -1.018 | 0.2 |
12 | 0.011 | 0.714 | -1.045 | -0.518 |
13 | -0.425 | 0.215 | -0.93 | 0.537 |
14 | -0.271 | -0.31 | -0.735 | 0.705 |
P-value | Threshold |
---|---|
0.001 | 2.91571 |
0.0005 | 4.33296 |
0.0001 | 7.19646 |