| Motif | NKX28.H12INVIVO.0.SM.D |
| Gene (human) | NKX2-8 (GeneCards) |
| Gene synonyms (human) | NKX-2.8, NKX2G, NKX2H |
| Gene (mouse) | Nkx2-8 |
| Gene synonyms (mouse) | Nkx-2.9, Nkx2-9, Nkx2h |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | NKX28.H12INVIVO.0.SM.D |
| Gene (human) | NKX2-8 (GeneCards) |
| Gene synonyms (human) | NKX-2.8, NKX2G, NKX2H |
| Gene (mouse) | Nkx2-8 |
| Gene synonyms (mouse) | Nkx-2.9, Nkx2-9, Nkx2h |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 10 |
| Consensus | nWbAAGTGbn |
| GC content | 46.9% |
| Information content (bits; total / per base) | 9.799 / 0.98 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9479 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.969 | 0.95 | 0.95 | 0.924 | 0.889 | 0.865 |
| best | 0.989 | 0.981 | 0.982 | 0.972 | 0.953 | 0.939 | |
| Methyl HT-SELEX, 1 experiments | median | 0.989 | 0.981 | 0.982 | 0.972 | 0.953 | 0.939 |
| best | 0.989 | 0.981 | 0.982 | 0.972 | 0.953 | 0.939 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.962 | 0.937 | 0.939 | 0.909 | 0.864 | 0.84 |
| best | 0.986 | 0.977 | 0.978 | 0.965 | 0.953 | 0.936 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | NK2.2 {3.1.2.15} (TFClass) |
| TFClass ID | TFClass: 3.1.2.15.2 |
| HGNC | HGNC:16364 |
| MGI | MGI:1270158 |
| EntrezGene (human) | GeneID:26257 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18094 (SSTAR profile) |
| UniProt ID (human) | NKX28_HUMAN |
| UniProt ID (mouse) | NKX28_MOUSE |
| UniProt AC (human) | O15522 (TFClass) |
| UniProt AC (mouse) | O70584 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | NKX28.H12INVIVO.0.SM.D.pcm |
| PWM | NKX28.H12INVIVO.0.SM.D.pwm |
| PFM | NKX28.H12INVIVO.0.SM.D.pfm |
| Alignment | NKX28.H12INVIVO.0.SM.D.words.tsv |
| Threshold to P-value map | NKX28.H12INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | NKX28.H12INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | NKX28.H12INVIVO.0.SM.D_meme_format.meme |
| Transfac format | NKX28.H12INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1511.75 | 3380.75 | 2171.75 | 2414.75 |
| 02 | 1787.75 | 911.75 | 956.75 | 5822.75 |
| 03 | 407.0 | 3552.0 | 1486.0 | 4034.0 |
| 04 | 7265.0 | 0.0 | 2214.0 | 0.0 |
| 05 | 9479.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 9479.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 9479.0 |
| 08 | 1321.0 | 0.0 | 8155.0 | 3.0 |
| 09 | 362.5 | 3863.5 | 3444.5 | 1808.5 |
| 10 | 1862.75 | 2102.75 | 2741.75 | 2771.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.159 | 0.357 | 0.229 | 0.255 |
| 02 | 0.189 | 0.096 | 0.101 | 0.614 |
| 03 | 0.043 | 0.375 | 0.157 | 0.426 |
| 04 | 0.766 | 0.0 | 0.234 | 0.0 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1.0 |
| 08 | 0.139 | 0.0 | 0.86 | 0.0 |
| 09 | 0.038 | 0.408 | 0.363 | 0.191 |
| 10 | 0.197 | 0.222 | 0.289 | 0.292 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.449 | 0.355 | -0.087 | 0.019 |
| 02 | -0.282 | -0.954 | -0.906 | 0.898 |
| 03 | -1.757 | 0.404 | -0.466 | 0.532 |
| 04 | 1.12 | -6.943 | -0.068 | -6.943 |
| 05 | 1.386 | -6.943 | -6.943 | -6.943 |
| 06 | -6.943 | -6.943 | 1.386 | -6.943 |
| 07 | -6.943 | -6.943 | -6.943 | 1.386 |
| 08 | -0.584 | -6.943 | 1.235 | -6.106 |
| 09 | -1.872 | 0.488 | 0.374 | -0.27 |
| 10 | -0.24 | -0.119 | 0.146 | 0.157 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.31536 |
| 0.0005 | 6.191405 |
| 0.0001 | 7.50223 |