MotifNKX28.H12CORE.0.SM.B
Gene (human)NKX2-8
(GeneCards)
Gene synonyms (human)NKX-2.8, NKX2G, NKX2H
Gene (mouse)Nkx2-8
Gene synonyms (mouse)Nkx-2.9, Nkx2-9, Nkx2h
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnWbAAGTGbn
GC content46.9%
Information content (bits; total / per base)9.799 / 0.98
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9479

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.969 0.95 0.95 0.924 0.889 0.865
best 0.989 0.981 0.982 0.972 0.953 0.939
Methyl HT-SELEX, 1 experiments median 0.989 0.981 0.982 0.972 0.953 0.939
best 0.989 0.981 0.982 0.972 0.953 0.939
Non-Methyl HT-SELEX, 5 experiments median 0.962 0.937 0.939 0.909 0.864 0.84
best 0.986 0.977 0.978 0.965 0.953 0.936
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK2.2 {3.1.2.15} (TFClass)
TFClass IDTFClass: 3.1.2.15.2
HGNCHGNC:16364
MGIMGI:1270158
EntrezGene (human)GeneID:26257
(SSTAR profile)
EntrezGene (mouse)GeneID:18094
(SSTAR profile)
UniProt ID (human)NKX28_HUMAN
UniProt ID (mouse)NKX28_MOUSE
UniProt AC (human)O15522
(TFClass)
UniProt AC (mouse)O70584
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
PCM
ACGT
011511.753380.752171.752414.75
021787.75911.75956.755822.75
03407.03552.01486.04034.0
047265.00.02214.00.0
059479.00.00.00.0
060.00.09479.00.0
070.00.00.09479.0
081321.00.08155.03.0
09362.53863.53444.51808.5
101862.752102.752741.752771.75
PFM
ACGT
010.1590.3570.2290.255
020.1890.0960.1010.614
030.0430.3750.1570.426
040.7660.00.2340.0
051.00.00.00.0
060.00.01.00.0
070.00.00.01.0
080.1390.00.860.0
090.0380.4080.3630.191
100.1970.2220.2890.292
PWM
ACGT
01-0.4490.355-0.0870.019
02-0.282-0.954-0.9060.898
03-1.7570.404-0.4660.532
041.12-6.943-0.068-6.943
051.386-6.943-6.943-6.943
06-6.943-6.9431.386-6.943
07-6.943-6.943-6.9431.386
08-0.584-6.9431.235-6.106
09-1.8720.4880.374-0.27
10-0.24-0.1190.1460.157
Standard thresholds
P-value Threshold
0.001 5.31536
0.0005 6.191405
0.0001 7.50223