Motif | NKX25.H12CORE.1.P.B |
Gene (human) | NKX2-5 (GeneCards) |
Gene synonyms (human) | CSX, NKX2.5, NKX2E |
Gene (mouse) | Nkx2-5 |
Gene synonyms (mouse) | Csx, Nkx-2.5, Nkx2e |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif | NKX25.H12CORE.1.P.B |
Gene (human) | NKX2-5 (GeneCards) |
Gene synonyms (human) | CSX, NKX2.5, NKX2E |
Gene (mouse) | Nkx2-5 |
Gene synonyms (mouse) | Csx, Nkx-2.5, Nkx2e |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | B |
Motif length | 13 |
Consensus | ddSTGhTGASARv |
GC content | 51.4% |
Information content (bits; total / per base) | 10.787 / 0.83 |
Data sources | ChIP-Seq |
Aligned words | 1002 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 2 (14) | 0.844 | 0.855 | 0.746 | 0.766 | 0.806 | 0.812 | 2.724 | 2.777 | 109.008 | 124.77 |
Mouse | 7 (29) | 0.653 | 0.821 | 0.53 | 0.732 | 0.619 | 0.795 | 1.666 | 2.671 | 15.208 | 79.301 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 2 experiments | median | 0.529 | 0.515 | 0.53 | 0.516 | 0.526 | 0.514 |
best | 0.545 | 0.524 | 0.541 | 0.522 | 0.533 | 0.519 | |
Methyl HT-SELEX, 1 experiments | median | 0.513 | 0.507 | 0.518 | 0.509 | 0.518 | 0.509 |
best | 0.513 | 0.507 | 0.518 | 0.509 | 0.518 | 0.509 | |
Non-Methyl HT-SELEX, 1 experiments | median | 0.545 | 0.524 | 0.541 | 0.522 | 0.533 | 0.519 |
best | 0.545 | 0.524 | 0.541 | 0.522 | 0.533 | 0.519 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | NK4 {3.1.2.17} (TFClass) |
TFClass ID | TFClass: 3.1.2.17.2 |
HGNC | HGNC:2488 |
MGI | MGI:97350 |
EntrezGene (human) | GeneID:1482 (SSTAR profile) |
EntrezGene (mouse) | GeneID:18091 (SSTAR profile) |
UniProt ID (human) | NKX25_HUMAN |
UniProt ID (mouse) | NKX25_MOUSE |
UniProt AC (human) | P52952 (TFClass) |
UniProt AC (mouse) | P42582 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 2 human, 7 mouse |
HT-SELEX | 1 |
Methyl-HT-SELEX | 1 |
PCM | NKX25.H12CORE.1.P.B.pcm |
PWM | NKX25.H12CORE.1.P.B.pwm |
PFM | NKX25.H12CORE.1.P.B.pfm |
Alignment | NKX25.H12CORE.1.P.B.words.tsv |
Threshold to P-value map | NKX25.H12CORE.1.P.B.thr |
Motif in other formats | |
JASPAR format | NKX25.H12CORE.1.P.B_jaspar_format.txt |
MEME format | NKX25.H12CORE.1.P.B_meme_format.meme |
Transfac format | NKX25.H12CORE.1.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 444.0 | 98.0 | 334.0 | 126.0 |
02 | 320.0 | 91.0 | 439.0 | 152.0 |
03 | 85.0 | 265.0 | 584.0 | 68.0 |
04 | 83.0 | 32.0 | 50.0 | 837.0 |
05 | 21.0 | 41.0 | 933.0 | 7.0 |
06 | 239.0 | 333.0 | 124.0 | 306.0 |
07 | 55.0 | 10.0 | 67.0 | 870.0 |
08 | 31.0 | 7.0 | 963.0 | 1.0 |
09 | 943.0 | 17.0 | 20.0 | 22.0 |
10 | 173.0 | 547.0 | 252.0 | 30.0 |
11 | 819.0 | 4.0 | 38.0 | 141.0 |
12 | 145.0 | 24.0 | 730.0 | 103.0 |
13 | 195.0 | 295.0 | 398.0 | 114.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.443 | 0.098 | 0.333 | 0.126 |
02 | 0.319 | 0.091 | 0.438 | 0.152 |
03 | 0.085 | 0.264 | 0.583 | 0.068 |
04 | 0.083 | 0.032 | 0.05 | 0.835 |
05 | 0.021 | 0.041 | 0.931 | 0.007 |
06 | 0.239 | 0.332 | 0.124 | 0.305 |
07 | 0.055 | 0.01 | 0.067 | 0.868 |
08 | 0.031 | 0.007 | 0.961 | 0.001 |
09 | 0.941 | 0.017 | 0.02 | 0.022 |
10 | 0.173 | 0.546 | 0.251 | 0.03 |
11 | 0.817 | 0.004 | 0.038 | 0.141 |
12 | 0.145 | 0.024 | 0.729 | 0.103 |
13 | 0.195 | 0.294 | 0.397 | 0.114 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.569 | -0.928 | 0.286 | -0.68 |
02 | 0.243 | -1.001 | 0.558 | -0.495 |
03 | -1.068 | 0.056 | 0.843 | -1.286 |
04 | -1.091 | -2.012 | -1.584 | 1.202 |
05 | -2.407 | -1.775 | 1.31 | -3.364 |
06 | -0.047 | 0.283 | -0.696 | 0.199 |
07 | -1.492 | -3.068 | -1.3 | 1.24 |
08 | -2.042 | -3.364 | 1.342 | -4.527 |
09 | 1.321 | -2.6 | -2.452 | -2.364 |
10 | -0.367 | 0.777 | 0.006 | -2.073 |
11 | 1.18 | -3.785 | -1.848 | -0.569 |
12 | -0.542 | -2.283 | 1.065 | -0.879 |
13 | -0.249 | 0.162 | 0.46 | -0.779 |
P-value | Threshold |
---|---|
0.001 | 4.53411 |
0.0005 | 5.42071 |
0.0001 | 7.24336 |