| Motif | NKX23.H12INVITRO.0.SM.B |
| Gene (human) | NKX2-3 (GeneCards) |
| Gene synonyms (human) | NKX23, NKX2C |
| Gene (mouse) | Nkx2-3 |
| Gene synonyms (mouse) | Nkx-2.3, Nkx2c |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | NKX23.H12INVITRO.0.SM.B |
| Gene (human) | NKX2-3 (GeneCards) |
| Gene synonyms (human) | NKX23, NKX2C |
| Gene (mouse) | Nkx2-3 |
| Gene synonyms (mouse) | Nkx-2.3, Nkx2c |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 10 |
| Consensus | nhYAAGTGbn |
| GC content | 44.01% |
| Information content (bits; total / per base) | 10.6 / 1.06 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9973 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 10 experiments | median | 0.964 | 0.938 | 0.944 | 0.915 | 0.876 | 0.85 |
| best | 0.988 | 0.98 | 0.984 | 0.973 | 0.978 | 0.964 | |
| Methyl HT-SELEX, 3 experiments | median | 0.971 | 0.948 | 0.962 | 0.935 | 0.933 | 0.907 |
| best | 0.973 | 0.953 | 0.964 | 0.94 | 0.937 | 0.908 | |
| Non-Methyl HT-SELEX, 7 experiments | median | 0.865 | 0.83 | 0.731 | 0.716 | 0.627 | 0.635 |
| best | 0.988 | 0.98 | 0.984 | 0.973 | 0.978 | 0.964 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | NK4 {3.1.2.17} (TFClass) |
| TFClass ID | TFClass: 3.1.2.17.1 |
| HGNC | HGNC:7836 |
| MGI | MGI:97348 |
| EntrezGene (human) | GeneID:159296 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18089 (SSTAR profile) |
| UniProt ID (human) | NKX23_HUMAN |
| UniProt ID (mouse) | NKX23_MOUSE |
| UniProt AC (human) | Q8TAU0 (TFClass) |
| UniProt AC (mouse) | P97334 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 7 |
| Methyl-HT-SELEX | 3 |
| PCM | NKX23.H12INVITRO.0.SM.B.pcm |
| PWM | NKX23.H12INVITRO.0.SM.B.pwm |
| PFM | NKX23.H12INVITRO.0.SM.B.pfm |
| Alignment | NKX23.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | NKX23.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NKX23.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | NKX23.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | NKX23.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1706.0 | 3023.0 | 3129.0 | 2115.0 |
| 02 | 1741.0 | 1160.0 | 1156.0 | 5916.0 |
| 03 | 185.0 | 2708.0 | 720.0 | 6360.0 |
| 04 | 9626.0 | 0.0 | 347.0 | 0.0 |
| 05 | 9973.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 9971.0 | 2.0 |
| 07 | 49.0 | 1.0 | 44.0 | 9879.0 |
| 08 | 1116.0 | 3.0 | 8847.0 | 7.0 |
| 09 | 614.5 | 3884.5 | 3968.5 | 1505.5 |
| 10 | 2161.5 | 2786.5 | 2139.5 | 2885.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.171 | 0.303 | 0.314 | 0.212 |
| 02 | 0.175 | 0.116 | 0.116 | 0.593 |
| 03 | 0.019 | 0.272 | 0.072 | 0.638 |
| 04 | 0.965 | 0.0 | 0.035 | 0.0 |
| 05 | 1.0 | 0.0 | 0.0 | 0.0 |
| 06 | 0.0 | 0.0 | 1.0 | 0.0 |
| 07 | 0.005 | 0.0 | 0.004 | 0.991 |
| 08 | 0.112 | 0.0 | 0.887 | 0.001 |
| 09 | 0.062 | 0.39 | 0.398 | 0.151 |
| 10 | 0.217 | 0.279 | 0.215 | 0.289 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.379 | 0.193 | 0.227 | -0.164 |
| 02 | -0.359 | -0.764 | -0.768 | 0.864 |
| 03 | -2.59 | 0.083 | -1.24 | 0.936 |
| 04 | 1.35 | -6.989 | -1.966 | -6.989 |
| 05 | 1.386 | -6.989 | -6.989 | -6.989 |
| 06 | -6.989 | -6.989 | 1.385 | -6.363 |
| 07 | -3.885 | -6.628 | -3.987 | 1.376 |
| 08 | -0.803 | -6.154 | 1.266 | -5.592 |
| 09 | -1.398 | 0.443 | 0.464 | -0.504 |
| 10 | -0.143 | 0.111 | -0.153 | 0.146 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.652785 |
| 0.0005 | 5.87088 |
| 0.0001 | 7.71357 |