MotifNKX23.H12CORE.0.SM.B
Gene (human)NKX2-3
(GeneCards)
Gene synonyms (human)NKX23, NKX2C
Gene (mouse)Nkx2-3
Gene synonyms (mouse)Nkx-2.3, Nkx2c
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnhYAAGTGbn
GC content44.01%
Information content (bits; total / per base)10.6 / 1.06
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9973

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 10 experiments median 0.964 0.938 0.944 0.915 0.876 0.85
best 0.988 0.98 0.984 0.973 0.978 0.964
Methyl HT-SELEX, 3 experiments median 0.971 0.948 0.962 0.935 0.933 0.907
best 0.973 0.953 0.964 0.94 0.937 0.908
Non-Methyl HT-SELEX, 7 experiments median 0.865 0.83 0.731 0.716 0.627 0.635
best 0.988 0.98 0.984 0.973 0.978 0.964
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK4 {3.1.2.17} (TFClass)
TFClass IDTFClass: 3.1.2.17.1
HGNCHGNC:7836
MGIMGI:97348
EntrezGene (human)GeneID:159296
(SSTAR profile)
EntrezGene (mouse)GeneID:18089
(SSTAR profile)
UniProt ID (human)NKX23_HUMAN
UniProt ID (mouse)NKX23_MOUSE
UniProt AC (human)Q8TAU0
(TFClass)
UniProt AC (mouse)P97334
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 7
Methyl-HT-SELEX 3
PCM
ACGT
011706.03023.03129.02115.0
021741.01160.01156.05916.0
03185.02708.0720.06360.0
049626.00.0347.00.0
059973.00.00.00.0
060.00.09971.02.0
0749.01.044.09879.0
081116.03.08847.07.0
09614.53884.53968.51505.5
102161.52786.52139.52885.5
PFM
ACGT
010.1710.3030.3140.212
020.1750.1160.1160.593
030.0190.2720.0720.638
040.9650.00.0350.0
051.00.00.00.0
060.00.01.00.0
070.0050.00.0040.991
080.1120.00.8870.001
090.0620.390.3980.151
100.2170.2790.2150.289
PWM
ACGT
01-0.3790.1930.227-0.164
02-0.359-0.764-0.7680.864
03-2.590.083-1.240.936
041.35-6.989-1.966-6.989
051.386-6.989-6.989-6.989
06-6.989-6.9891.385-6.363
07-3.885-6.628-3.9871.376
08-0.803-6.1541.266-5.592
09-1.3980.4430.464-0.504
10-0.1430.111-0.1530.146
Standard thresholds
P-value Threshold
0.001 4.652785
0.0005 5.87088
0.0001 7.71357