NKX22.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NKX22.H12INVITRO.0.P.D
Gene (human)	NKX2-2 (GeneCards)
Gene synonyms (human)	NKX2.2, NKX2B
Gene (mouse)	Nkx2-2
Gene synonyms (mouse)	Nkx-2.2, Nkx2b
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	10
Consensus	nYbRAGWGbn
GC content	51.9%
Information content (bits; total / per base)	7.067 / 0.707
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	5 (35)	0.755	0.835	0.582	0.69	0.648	0.71	1.485	1.758	69.721	155.444

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	NK2.2 {3.1.2.15} (TFClass)
TFClass ID	TFClass: 3.1.2.15.1
HGNC	HGNC:7835
MGI	MGI:97347
EntrezGene (human)	GeneID:4821 (SSTAR profile)
EntrezGene (mouse)	GeneID:18088 (SSTAR profile)
UniProt ID (human)	NKX22_HUMAN
UniProt ID (mouse)	NKX22_MOUSE
UniProt AC (human)	O95096 (TFClass)
UniProt AC (mouse)	P42586 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 5 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	NKX22.H12INVITRO.0.P.D.pcm
PWM	NKX22.H12INVITRO.0.P.D.pwm
PFM	NKX22.H12INVITRO.0.P.D.pfm
Alignment	NKX22.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	NKX22.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	NKX22.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	NKX22.H12INVITRO.0.P.D_meme_format.meme
Transfac format	NKX22.H12INVITRO.0.P.D_transfac_format.txt
Homer format	NKX22.H12INVITRO.0.P.D_homer_format_0.001.txt NKX22.H12INVITRO.0.P.D_homer_format_0.0005.txt NKX22.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	139.0	335.0	256.0	269.0
02	100.0	206.0	80.0	613.0
03	132.0	211.0	253.0	403.0
04	385.0	97.0	509.0	8.0
05	963.0	1.0	6.0	29.0
06	15.0	20.0	934.0	30.0
07	317.0	8.0	92.0	582.0
08	64.0	12.0	913.0	10.0
09	29.0	390.0	383.0	197.0
10	169.0	295.0	184.0	351.0

PFM

	A	C	G	T
01	0.139	0.335	0.256	0.269
02	0.1	0.206	0.08	0.614
03	0.132	0.211	0.253	0.403
04	0.385	0.097	0.51	0.008
05	0.964	0.001	0.006	0.029
06	0.015	0.02	0.935	0.03
07	0.317	0.008	0.092	0.583
08	0.064	0.012	0.914	0.01
09	0.029	0.39	0.383	0.197
10	0.169	0.295	0.184	0.351

PWM

	A	C	G	T
01	-0.581	0.292	0.025	0.074
02	-0.905	-0.191	-1.124	0.894
03	-0.632	-0.167	0.013	0.476
04	0.43	-0.935	0.708	-3.252
05	1.344	-4.524	-3.483	-2.102
06	-2.71	-2.449	1.314	-2.07
07	0.237	-3.252	-0.987	0.842
08	-1.342	-2.908	1.291	-3.065
09	-2.102	0.443	0.425	-0.235
10	-0.387	0.165	-0.303	0.338

Standard thresholds

P-value	Threshold
0.001	5.295255
0.0005	5.89934
0.0001	6.841635