MotifNKX22.H12CORE.0.P.B
Gene (human)NKX2-2
(GeneCards)
Gene synonyms (human)NKX2.2, NKX2B
Gene (mouse)Nkx2-2
Gene synonyms (mouse)Nkx-2.2, Nkx2b
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusnYbRAGWGbn
GC content51.9%
Information content (bits; total / per base)7.067 / 0.707
Data sourcesChIP-Seq
Aligned words999

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 5 (35) 0.755 0.835 0.582 0.69 0.648 0.71 1.485 1.758 69.721 155.444
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK2.2 {3.1.2.15} (TFClass)
TFClass IDTFClass: 3.1.2.15.1
HGNCHGNC:7835
MGIMGI:97347
EntrezGene (human)GeneID:4821
(SSTAR profile)
EntrezGene (mouse)GeneID:18088
(SSTAR profile)
UniProt ID (human)NKX22_HUMAN
UniProt ID (mouse)NKX22_MOUSE
UniProt AC (human)O95096
(TFClass)
UniProt AC (mouse)P42586
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 5 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01139.0335.0256.0269.0
02100.0206.080.0613.0
03132.0211.0253.0403.0
04385.097.0509.08.0
05963.01.06.029.0
0615.020.0934.030.0
07317.08.092.0582.0
0864.012.0913.010.0
0929.0390.0383.0197.0
10169.0295.0184.0351.0
PFM
ACGT
010.1390.3350.2560.269
020.10.2060.080.614
030.1320.2110.2530.403
040.3850.0970.510.008
050.9640.0010.0060.029
060.0150.020.9350.03
070.3170.0080.0920.583
080.0640.0120.9140.01
090.0290.390.3830.197
100.1690.2950.1840.351
PWM
ACGT
01-0.5810.2920.0250.074
02-0.905-0.191-1.1240.894
03-0.632-0.1670.0130.476
040.43-0.9350.708-3.252
051.344-4.524-3.483-2.102
06-2.71-2.4491.314-2.07
070.237-3.252-0.9870.842
08-1.342-2.9081.291-3.065
09-2.1020.4430.425-0.235
10-0.3870.165-0.3030.338
Standard thresholds
P-value Threshold
0.001 5.295255
0.0005 5.89934
0.0001 6.841635