MotifNKX21.H12CORE.0.P.B
Gene (human)NKX2-1
(GeneCards)
Gene synonyms (human)NKX2A, TITF1, TTF1
Gene (mouse)Nkx2-1
Gene synonyms (mouse)Nkx-2.1, Titf1, Ttf1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length11
ConsensusbWdRAGWGbhh
GC content50.61%
Information content (bits; total / per base)7.681 / 0.698
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (56) 0.833 0.913 0.707 0.821 0.742 0.822 1.96 2.461 115.012 293.398
Mouse 3 (19) 0.915 0.933 0.814 0.852 0.828 0.848 2.392 2.608 206.854 288.824
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNK2.1 {3.1.2.14} (TFClass)
TFClass IDTFClass: 3.1.2.14.1
HGNCHGNC:11825
MGIMGI:108067
EntrezGene (human)GeneID:7080
(SSTAR profile)
EntrezGene (mouse)GeneID:21869
(SSTAR profile)
UniProt ID (human)NKX21_HUMAN
UniProt ID (mouse)NKX21_MOUSE
UniProt AC (human)P43699
(TFClass)
UniProt AC (mouse)P50220
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 3 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
01132.0407.0234.0227.0
02221.0117.042.0620.0
03111.086.0290.0513.0
04174.065.0757.04.0
05949.01.013.037.0
0625.011.0963.01.0
07325.03.094.0578.0
08108.015.0842.035.0
0954.0326.0411.0209.0
10167.0325.0148.0360.0
11169.0283.0134.0414.0
PFM
ACGT
010.1320.4070.2340.227
020.2210.1170.0420.62
030.1110.0860.290.513
040.1740.0650.7570.004
050.9490.0010.0130.037
060.0250.0110.9630.001
070.3250.0030.0940.578
080.1080.0150.8420.035
090.0540.3260.4110.209
100.1670.3250.1480.36
110.1690.2830.1340.414
PWM
ACGT
01-0.6330.485-0.066-0.096
02-0.122-0.752-1.750.904
03-0.803-1.0540.1470.715
04-0.359-1.3281.103-3.783
051.329-4.525-2.839-1.872
06-2.243-2.9851.344-4.525
070.261-3.975-0.9670.834
08-0.83-2.7111.209-1.925
09-1.5080.2640.494-0.178
10-0.40.261-0.520.363
11-0.3880.123-0.6180.502
Standard thresholds
P-value Threshold
0.001 5.169665
0.0005 5.820935
0.0001 7.03679