MotifNGN2.H12INVITRO.1.SM.B
Gene (human)NEUROG2
(GeneCards)
Gene synonyms (human)ATOH4, BHLHA8, NGN2
Gene (mouse)Neurog2
Gene synonyms (mouse)Ath4a, Atoh4, Ngn2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusnRACATATGYYvhn
GC content37.0%
Information content (bits; total / per base)15.705 / 1.122
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2081

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 12 (84) 0.792 0.847 0.642 0.703 0.69 0.754 1.823 2.231 39.605 72.721
Mouse 5 (31) 0.832 0.872 0.651 0.708 0.727 0.784 1.931 2.227 77.921 130.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 5 experiments median 0.954 0.948 0.783 0.79 0.657 0.68
best 0.985 0.979 0.869 0.865 0.722 0.739
Methyl HT-SELEX, 1 experiments median 0.847 0.843 0.693 0.701 0.608 0.623
best 0.847 0.843 0.693 0.701 0.608 0.623
Non-Methyl HT-SELEX, 4 experiments median 0.959 0.953 0.789 0.796 0.659 0.683
best 0.985 0.979 0.869 0.865 0.722 0.739
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familyTal-related {1.2.3} (TFClass)
TF subfamilyNeurogenin-ATO {1.2.3.4} (TFClass)
TFClass IDTFClass: 1.2.3.4.6
HGNCHGNC:13805
MGIMGI:109619
EntrezGene (human)GeneID:63973
(SSTAR profile)
EntrezGene (mouse)GeneID:11924
(SSTAR profile)
UniProt ID (human)NGN2_HUMAN
UniProt ID (mouse)NGN2_MOUSE
UniProt AC (human)Q9H2A3
(TFClass)
UniProt AC (mouse)P70447
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 12 human, 5 mouse
HT-SELEX 4
Methyl-HT-SELEX 1
PCM
ACGT
01511.5452.5590.5526.5
021499.25206.25290.2585.25
031641.0149.0290.01.0
040.02081.00.00.0
052081.00.00.00.0
060.00.00.02081.0
072080.01.00.00.0
080.00.00.02081.0
090.00.02081.00.0
1034.0350.0236.01461.0
1157.01271.054.0699.0
121067.0407.0416.0191.0
13485.5708.5212.5674.5
14486.5526.5457.5610.5
PFM
ACGT
010.2460.2170.2840.253
020.720.0990.1390.041
030.7890.0720.1390.0
040.01.00.00.0
051.00.00.00.0
060.00.00.01.0
071.00.00.00.0
080.00.00.01.0
090.00.01.00.0
100.0160.1680.1130.702
110.0270.6110.0260.336
120.5130.1960.20.092
130.2330.340.1020.324
140.2340.2530.220.293
PWM
ACGT
01-0.017-0.1390.1260.012
021.056-0.92-0.581-1.79
031.146-1.241-0.582-5.19
04-5.6111.384-5.611-5.611
051.384-5.611-5.611-5.611
06-5.611-5.611-5.6111.384
071.383-5.19-5.611-5.611
08-5.611-5.611-5.6111.384
09-5.611-5.6111.384-5.611
10-2.677-0.395-0.7861.03
11-2.1820.891-2.2340.294
120.716-0.244-0.223-0.996
13-0.0690.308-0.890.259
14-0.0670.012-0.1280.159
Standard thresholds
P-value Threshold
0.001 0.609215
0.0005 2.12432
0.0001 5.64366