MotifNFKB2.H12INVITRO.0.PSM.A
Gene (human)NFKB2
(GeneCards)
Gene synonyms (human)LYT10
Gene (mouse)Nfkb2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusndRGGGGAAdYMCSdn
GC content55.3%
Information content (bits; total / per base)14.937 / 0.934
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words8027

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (10) 0.893 0.939 0.847 0.886 0.831 0.886 3.338 3.643 401.6 460.387

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.915 0.921 0.817 0.831 0.718 0.739
best 0.998 0.996 0.984 0.98 0.87 0.877
Methyl HT-SELEX, 1 experiments median 0.998 0.996 0.984 0.98 0.87 0.877
best 0.998 0.996 0.984 0.98 0.87 0.877
Non-Methyl HT-SELEX, 1 experiments median 0.833 0.846 0.65 0.682 0.565 0.601
best 0.833 0.846 0.65 0.682 0.565 0.601

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.957 0.625 0.923 0.603
batch 2 0.783 0.422 0.784 0.613
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFkappaB-related {6.1.1} (TFClass)
TF subfamilyNFkappaB p50-like {6.1.1.1} (TFClass)
TFClass IDTFClass: 6.1.1.1.2
HGNCHGNC:7795
MGIMGI:1099800
EntrezGene (human)GeneID:4791
(SSTAR profile)
EntrezGene (mouse)GeneID:18034
(SSTAR profile)
UniProt ID (human)NFKB2_HUMAN
UniProt ID (mouse)NFKB2_MOUSE
UniProt AC (human)Q00653
(TFClass)
UniProt AC (mouse)Q9WTK5
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012247.751641.752310.751826.75
023644.25913.251724.251745.25
034697.0585.01952.0793.0
0411.06.08004.06.0
051.01.08025.00.0
060.00.08002.025.0
072593.00.05410.024.0
087920.018.075.014.0
096302.0120.092.01513.0
101334.0493.01987.04213.0
11871.03314.0215.03627.0
122768.04937.0110.0212.0
13145.07528.0221.0133.0
14345.06357.0767.0558.0
151423.751374.751663.753564.75
161930.51730.51443.52922.5
PFM
ACGT
010.280.2050.2880.228
020.4540.1140.2150.217
030.5850.0730.2430.099
040.0010.0010.9970.001
050.00.01.00.0
060.00.00.9970.003
070.3230.00.6740.003
080.9870.0020.0090.002
090.7850.0150.0110.188
100.1660.0610.2480.525
110.1090.4130.0270.452
120.3450.6150.0140.026
130.0180.9380.0280.017
140.0430.7920.0960.07
150.1770.1710.2070.444
160.2410.2160.180.364
PWM
ACGT
010.113-0.2010.141-0.094
020.596-0.786-0.152-0.139
030.85-1.23-0.028-0.927
04-5.022-5.4951.383-5.495
05-6.427-6.4271.385-6.796
06-6.796-6.7961.382-4.3
070.256-6.7960.991-4.338
081.372-4.597-3.258-4.817
091.144-2.799-3.059-0.282
10-0.408-1.4-0.010.741
11-0.8330.501-2.2240.591
120.3210.9-2.885-2.238
13-2.6131.321-2.197-2.698
14-1.7551.152-0.96-1.277
15-0.343-0.378-0.1870.574
16-0.039-0.148-0.3290.376
Standard thresholds
P-value Threshold
0.001 1.93931
0.0005 3.44056
0.0001 6.46651