| Motif | NFIX.H12CORE.1.S.B |
| Gene (human) | NFIX (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfix |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | NFIX.H12CORE.1.S.B |
| Gene (human) | NFIX (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfix |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 8 |
| Consensus | dYGCCAAn |
| GC content | 54.98% |
| Information content (bits; total / per base) | 10.744 / 1.343 |
| Data sources | HT-SELEX |
| Aligned words | 7712 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.986 | 0.978 | 0.981 | 0.969 | 0.965 | 0.949 |
| best | 0.992 | 0.988 | 0.99 | 0.984 | 0.985 | 0.976 | |
| Methyl HT-SELEX, 1 experiments | median | 0.986 | 0.977 | 0.981 | 0.969 | 0.968 | 0.952 |
| best | 0.986 | 0.977 | 0.981 | 0.969 | 0.968 | 0.952 | |
| Non-Methyl HT-SELEX, 5 experiments | median | 0.986 | 0.978 | 0.981 | 0.969 | 0.962 | 0.947 |
| best | 0.992 | 0.988 | 0.99 | 0.984 | 0.985 | 0.976 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.865 | 0.436 | 0.848 | 0.537 |
| batch 2 | 0.686 | 0.401 | 0.724 | 0.506 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | NF-1 {7.1.2} (TFClass) |
| TF subfamily | {7.1.2.0} (TFClass) |
| TFClass ID | TFClass: 7.1.2.0.4 |
| HGNC | HGNC:7788 |
| MGI | MGI:97311 |
| EntrezGene (human) | GeneID:4784 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18032 (SSTAR profile) |
| UniProt ID (human) | NFIX_HUMAN |
| UniProt ID (mouse) | NFIX_MOUSE |
| UniProt AC (human) | Q14938 (TFClass) |
| UniProt AC (mouse) | P70257 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 5 |
| Methyl-HT-SELEX | 1 |
| PCM | NFIX.H12CORE.1.S.B.pcm |
| PWM | NFIX.H12CORE.1.S.B.pwm |
| PFM | NFIX.H12CORE.1.S.B.pfm |
| Alignment | NFIX.H12CORE.1.S.B.words.tsv |
| Threshold to P-value map | NFIX.H12CORE.1.S.B.thr |
| Motif in other formats | |
| JASPAR format | NFIX.H12CORE.1.S.B_jaspar_format.txt |
| MEME format | NFIX.H12CORE.1.S.B_meme_format.meme |
| Transfac format | NFIX.H12CORE.1.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1547.5 | 1464.5 | 3172.5 | 1527.5 |
| 02 | 1044.25 | 1095.25 | 83.25 | 5489.25 |
| 03 | 0.0 | 0.0 | 7712.0 | 0.0 |
| 04 | 0.0 | 7712.0 | 0.0 | 0.0 |
| 05 | 0.0 | 7712.0 | 0.0 | 0.0 |
| 06 | 7712.0 | 0.0 | 0.0 | 0.0 |
| 07 | 7489.0 | 0.0 | 223.0 | 0.0 |
| 08 | 1795.0 | 2223.0 | 2522.0 | 1172.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.201 | 0.19 | 0.411 | 0.198 |
| 02 | 0.135 | 0.142 | 0.011 | 0.712 |
| 03 | 0.0 | 0.0 | 1.0 | 0.0 |
| 04 | 0.0 | 1.0 | 0.0 | 0.0 |
| 05 | 0.0 | 1.0 | 0.0 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.971 | 0.0 | 0.029 | 0.0 |
| 08 | 0.233 | 0.288 | 0.327 | 0.152 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.22 | -0.275 | 0.498 | -0.233 |
| 02 | -0.612 | -0.565 | -3.117 | 1.046 |
| 03 | -6.76 | -6.76 | 1.385 | -6.76 |
| 04 | -6.76 | 1.385 | -6.76 | -6.76 |
| 05 | -6.76 | 1.385 | -6.76 | -6.76 |
| 06 | 1.385 | -6.76 | -6.76 | -6.76 |
| 07 | 1.356 | -6.76 | -2.148 | -6.76 |
| 08 | -0.071 | 0.142 | 0.268 | -0.497 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.80171 |
| 0.0005 | 6.207055 |
| 0.0001 | 7.90584 |