NFIL3.H12CORE.1.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFIL3.H12CORE.1.S.B
Gene (human)	NFIL3 (GeneCards)
Gene synonyms (human)	E4BP4, IL3BP1
Gene (mouse)	Nfil3
Gene synonyms (mouse)	E4bp4
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	18
Consensus	ddRTTACGTAAYnnnnnn
GC content	43.31%
Information content (bits; total / per base)	15.229 / 0.846
Data sources	HT-SELEX
Aligned words	9646

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.912	0.942	0.881	0.911	0.933	0.958	4.114	4.334	491.496	534.745
Mouse	1 (4)	0.842	0.879	0.81	0.856	0.848	0.889	3.476	3.791	318.101	381.824

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.905	0.906	0.82	0.832	0.727	0.75
Non-Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.998	0.996	0.888	0.905

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	PAR {1.1.8.2} (TFClass)
TFClass ID	TFClass: 1.1.8.2.3
HGNC	HGNC:7787
MGI	MGI:109495
EntrezGene (human)	GeneID:4783 (SSTAR profile)
EntrezGene (mouse)	GeneID:18030 (SSTAR profile)
UniProt ID (human)	NFIL3_HUMAN
UniProt ID (mouse)	NFIL3_MOUSE
UniProt AC (human)	Q16649 (TFClass)
UniProt AC (mouse)	O08750 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 1 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	NFIL3.H12CORE.1.S.B.pcm
PWM	NFIL3.H12CORE.1.S.B.pwm
PFM	NFIL3.H12CORE.1.S.B.pfm
Alignment	NFIL3.H12CORE.1.S.B.words.tsv
Threshold to P-value map	NFIL3.H12CORE.1.S.B.thr
Motif in other formats
JASPAR format	NFIL3.H12CORE.1.S.B_jaspar_format.txt
MEME format	NFIL3.H12CORE.1.S.B_meme_format.meme
Transfac format	NFIL3.H12CORE.1.S.B_transfac_format.txt
Homer format	NFIL3.H12CORE.1.S.B_homer_format_0.001.txt NFIL3.H12CORE.1.S.B_homer_format_0.0005.txt NFIL3.H12CORE.1.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1892.5	1751.5	4063.5	1938.5
02	1567.75	1373.75	4469.75	2234.75
03	4217.0	743.0	4627.0	59.0
04	5.0	2.0	1.0	9638.0
05	0.0	0.0	1570.0	8076.0
06	9288.0	0.0	358.0	0.0
07	0.0	8640.0	0.0	1006.0
08	755.0	0.0	8891.0	0.0
09	0.0	221.0	0.0	9425.0
10	8544.0	1101.0	1.0	0.0
11	9645.0	1.0	0.0	0.0
12	35.0	2805.0	1657.0	5149.0
13	3048.0	2950.0	1907.0	1741.0
14	2683.0	2064.0	2989.0	1910.0
15	1748.0	2950.0	2718.0	2230.0
16	1724.0	3346.0	2507.0	2069.0
17	1720.75	3424.75	2499.75	2000.75
18	1957.0	3178.0	2390.0	2121.0

PFM

	A	C	G	T
01	0.196	0.182	0.421	0.201
02	0.163	0.142	0.463	0.232
03	0.437	0.077	0.48	0.006
04	0.001	0.0	0.0	0.999
05	0.0	0.0	0.163	0.837
06	0.963	0.0	0.037	0.0
07	0.0	0.896	0.0	0.104
08	0.078	0.0	0.922	0.0
09	0.0	0.023	0.0	0.977
10	0.886	0.114	0.0	0.0
11	1.0	0.0	0.0	0.0
12	0.004	0.291	0.172	0.534
13	0.316	0.306	0.198	0.18
14	0.278	0.214	0.31	0.198
15	0.181	0.306	0.282	0.231
16	0.179	0.347	0.26	0.214
17	0.178	0.355	0.259	0.207
18	0.203	0.329	0.248	0.22

PWM

	A	C	G	T
01	-0.242	-0.319	0.521	-0.218
02	-0.43	-0.562	0.617	-0.076
03	0.558	-1.175	0.651	-3.673
04	-5.802	-6.332	-6.597	1.385
05	-6.959	-6.959	-0.429	1.208
06	1.348	-6.959	-1.902	-6.959
07	-6.959	1.275	-6.959	-0.873
08	-1.159	-6.959	1.304	-6.959
09	-6.959	-2.38	-6.959	1.362
10	1.264	-0.783	-6.597	-6.959
11	1.385	-6.597	-6.959	-6.959
12	-4.17	0.151	-0.375	0.758
13	0.234	0.201	-0.234	-0.325
14	0.107	-0.155	0.215	-0.233
15	-0.321	0.201	0.12	-0.078
16	-0.335	0.327	0.039	-0.153
17	-0.337	0.35	0.036	-0.187
18	-0.209	0.276	-0.009	-0.128

Standard thresholds

P-value	Threshold
0.001	0.36246
0.0005	2.11601
0.0001	6.12906