| Motif | NFIC.H12RSNP.0.PSM.A |
| Gene (human) | NFIC (GeneCards) |
| Gene synonyms (human) | NFI |
| Gene (mouse) | Nfic |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | NFIC.H12RSNP.0.PSM.A |
| Gene (human) | NFIC (GeneCards) |
| Gene synonyms (human) | NFI |
| Gene (mouse) | Nfic |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 17 |
| Consensus | nYTGGCdnCdhGCCARn |
| GC content | 55.28% |
| Information content (bits; total / per base) | 16.689 / 0.982 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2493 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 6 (41) | 0.865 | 0.98 | 0.807 | 0.976 | 0.819 | 0.975 | 2.902 | 6.267 | 205.959 | 882.886 |
| Mouse | 2 (6) | 0.761 | 0.836 | 0.693 | 0.761 | 0.7 | 0.78 | 2.382 | 2.61 | 9.387 | 33.108 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 5.865 | 15.684 | 0.169 | 0.069 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.984 | 0.941 | 0.965 | 0.628 |
| batch 2 | 0.882 | 0.699 | 0.882 | 0.738 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | NF-1 {7.1.2} (TFClass) |
| TF subfamily | {7.1.2.0} (TFClass) |
| TFClass ID | TFClass: 7.1.2.0.3 |
| HGNC | HGNC:7786 |
| MGI | MGI:109591 |
| EntrezGene (human) | GeneID:4782 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18029 (SSTAR profile) |
| UniProt ID (human) | NFIC_HUMAN |
| UniProt ID (mouse) | NFIC_MOUSE |
| UniProt AC (human) | P08651 (TFClass) |
| UniProt AC (mouse) | P70255 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 6 human, 2 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | NFIC.H12RSNP.0.PSM.A.pcm |
| PWM | NFIC.H12RSNP.0.PSM.A.pwm |
| PFM | NFIC.H12RSNP.0.PSM.A.pfm |
| Alignment | NFIC.H12RSNP.0.PSM.A.words.tsv |
| Threshold to P-value map | NFIC.H12RSNP.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | NFIC.H12RSNP.0.PSM.A_jaspar_format.txt |
| MEME format | NFIC.H12RSNP.0.PSM.A_meme_format.meme |
| Transfac format | NFIC.H12RSNP.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 508.5 | 791.5 | 662.5 | 530.5 |
| 02 | 125.25 | 507.25 | 58.25 | 1802.25 |
| 03 | 44.0 | 30.0 | 26.0 | 2393.0 |
| 04 | 35.0 | 32.0 | 2404.0 | 22.0 |
| 05 | 38.0 | 34.0 | 2388.0 | 33.0 |
| 06 | 223.0 | 2207.0 | 21.0 | 42.0 |
| 07 | 1354.0 | 156.0 | 592.0 | 391.0 |
| 08 | 770.0 | 605.0 | 352.0 | 766.0 |
| 09 | 0.0 | 1379.0 | 0.0 | 1114.0 |
| 10 | 657.0 | 302.0 | 903.0 | 631.0 |
| 11 | 374.0 | 573.0 | 259.0 | 1287.0 |
| 12 | 27.0 | 26.0 | 2238.0 | 202.0 |
| 13 | 14.0 | 2418.0 | 34.0 | 27.0 |
| 14 | 28.0 | 2407.0 | 20.0 | 38.0 |
| 15 | 2400.0 | 44.0 | 23.0 | 26.0 |
| 16 | 1845.75 | 67.75 | 491.75 | 87.75 |
| 17 | 615.5 | 620.5 | 755.5 | 501.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.204 | 0.317 | 0.266 | 0.213 |
| 02 | 0.05 | 0.203 | 0.023 | 0.723 |
| 03 | 0.018 | 0.012 | 0.01 | 0.96 |
| 04 | 0.014 | 0.013 | 0.964 | 0.009 |
| 05 | 0.015 | 0.014 | 0.958 | 0.013 |
| 06 | 0.089 | 0.885 | 0.008 | 0.017 |
| 07 | 0.543 | 0.063 | 0.237 | 0.157 |
| 08 | 0.309 | 0.243 | 0.141 | 0.307 |
| 09 | 0.0 | 0.553 | 0.0 | 0.447 |
| 10 | 0.264 | 0.121 | 0.362 | 0.253 |
| 11 | 0.15 | 0.23 | 0.104 | 0.516 |
| 12 | 0.011 | 0.01 | 0.898 | 0.081 |
| 13 | 0.006 | 0.97 | 0.014 | 0.011 |
| 14 | 0.011 | 0.966 | 0.008 | 0.015 |
| 15 | 0.963 | 0.018 | 0.009 | 0.01 |
| 16 | 0.74 | 0.027 | 0.197 | 0.035 |
| 17 | 0.247 | 0.249 | 0.303 | 0.201 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.203 | 0.238 | 0.061 | -0.161 |
| 02 | -1.592 | -0.205 | -2.34 | 1.06 |
| 03 | -2.61 | -2.974 | -3.107 | 1.343 |
| 04 | -2.828 | -2.913 | 1.348 | -3.262 |
| 05 | -2.75 | -2.856 | 1.341 | -2.884 |
| 06 | -1.022 | 1.262 | -3.305 | -2.655 |
| 07 | 0.774 | -1.376 | -0.051 | -0.464 |
| 08 | 0.211 | -0.03 | -0.569 | 0.206 |
| 09 | -5.768 | 0.792 | -5.768 | 0.579 |
| 10 | 0.053 | -0.721 | 0.37 | 0.012 |
| 11 | -0.509 | -0.084 | -0.874 | 0.724 |
| 12 | -3.072 | -3.107 | 1.276 | -1.12 |
| 13 | -3.668 | 1.353 | -2.856 | -3.072 |
| 14 | -3.038 | 1.349 | -3.349 | -2.75 |
| 15 | 1.346 | -2.61 | -3.221 | -3.107 |
| 16 | 1.084 | -2.194 | -0.236 | -1.942 |
| 17 | -0.012 | -0.004 | 0.192 | -0.217 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.86091 |
| 0.0005 | 3.16966 |
| 0.0001 | 5.88421 |